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酗酒风险处于平均水平和高于平均水平的非酒精性年轻男性之间的P300差异:分心和任务模式的影响。

P300 differences between non-alcoholic young men at average and above-average risk for alcoholism: effects of distraction and task modality.

作者信息

Bauer L, Hesselbrock V M, O'Connor S, Roberts L

机构信息

Department of Psychiatry, University of Connecticut School of Medicine, Farmington.

出版信息

Prog Neuropsychopharmacol Biol Psychiatry. 1994 Mar;18(2):263-77. doi: 10.1016/0278-5846(94)90058-2.

DOI:10.1016/0278-5846(94)90058-2
PMID:8208977
Abstract
  1. P300 event-related electroencephalographic potentials were recorded from 79 young adult males, cross-classified with respect to the presence/absence of a family history of alcoholism (FHA) and the presence/absence of a personal history of antisocial personality (ASP) disorder. P300s were elicited using visual and auditory oddball tasks. Each oddball task was repeated with a tracking task added as a distractor. 2. In general, distraction increased the latencies and reduced the amplitudes of P300s elicited by the oddball stimuli. The P300 latency increase occurred only in low risk ASP- and FHA- groups. There was no adaptive increase in P300 latency in the higher risk ASP+ and FHA+ groups. 3. Group differences in P300 were restricted to visual tasks. No interpretable group differences in P300 latency or amplitude were found during the auditory tasks.
摘要
  1. 从79名年轻成年男性中记录了P300事件相关脑电图电位,根据是否有酒精中毒家族史(FHA)以及是否有反社会人格(ASP)障碍个人史进行交叉分类。使用视觉和听觉oddball任务诱发P300。每个oddball任务都重复进行,并添加一个跟踪任务作为干扰项。2. 一般来说,干扰会增加oddball刺激诱发的P300的潜伏期并降低其波幅。P300潜伏期增加仅发生在低风险的ASP-和FHA-组中。高风险的ASP+和FHA+组中P300潜伏期没有适应性增加。3. P300的组间差异仅限于视觉任务。在听觉任务期间,未发现P300潜伏期或波幅有可解释的组间差异。

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