University of Wisconsin-Madison, Psychology Department, United States.
University of Wisconsin-Madison, Psychology Department, United States.
Biol Psychol. 2014 Feb;96:86-93. doi: 10.1016/j.biopsycho.2013.12.005. Epub 2013 Dec 16.
The P3 amplitude reduction is one of the most common correlates of externalizing. However, few studies have used experimental manipulations designed to challenge different cognitive functions in order to clarify the processes that impact this reduction. To examine factors moderating P3 amplitude in trait externalizing, we administered an n-back task that manipulated cognitive control demands, working memory load, and incentives to a sample of male offenders. Offenders with high trait externalizing scores did not display a global reduction in P3 amplitude. Rather, the negative association between trait externalizing and P3 amplitude was specific to trials involving inhibition of a dominant response during infrequent stimuli, in the context of low working memory load, and incentives for performance. In addition, we discuss the potential implications of these findings for externalizing-related psychopathologies. The results complement and expand previous work on the process-level dysfunction contributing to externalizing-related deficits in P3.
P3 波幅降低是外化问题的最常见相关因素之一。然而，很少有研究采用旨在挑战不同认知功能的实验操作来阐明影响这种降低的过程。为了研究特质外化的调节因素，我们对一组男性罪犯进行了 n 回任务，该任务改变了认知控制需求、工作记忆负荷和激励因素。特质外化得分高的罪犯并没有表现出 P3 波幅的全面降低。相反，特质外化与 P3 波幅之间的负相关仅针对在低工作记忆负荷和绩效激励的情况下，在罕见刺激中抑制主导反应的试验。此外，我们还讨论了这些发现对外化相关精神病理的潜在影响。这些结果补充并扩展了之前关于导致 P3 与外化相关缺陷的过程水平功能障碍的研究。
