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失神发作的预后因素。

Prognostic factors in absence seizures.

作者信息

Sato S, Dreifuss F E, Penry J K

出版信息

Neurology. 1976 Aug;26(8):788-96. doi: 10.1212/wnl.26.8.788.

DOI:10.1212/wnl.26.8.788
PMID:821006
Abstract

A prospective follow-up study was conducted on 48 epileptic patients (22 males and 26 females) who had participated in a collaborative study of absence seizures about 7 years earlier. Multivariate analysis showed that the significant prognostic factors for absence seizures were normal or above normal intelligence and normal electroencephalographic background activity. For any seizure type, significant prognostic factors were a negative history of generalized tonic-clonic seizures, normal or above normal intelligence, and a negative family history of seizure disorders. Nearly 90 percent of the patients with all significant prognostic factors for both absence seizures and seizures of all types ceased having seizures.

摘要

对约7年前参与失神发作协作研究的48例癫痫患者(22例男性和26例女性)进行了前瞻性随访研究。多变量分析显示,失神发作的显著预后因素为智力正常或高于正常以及脑电图背景活动正常。对于任何癫痫发作类型,显著预后因素为全身强直阵挛性发作阴性病史、智力正常或高于正常以及癫痫障碍家族史阴性。具有失神发作和所有类型癫痫发作的所有显著预后因素的患者中,近90%停止发作。

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引用本文的文献

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Outcome of Absence Epilepsy With Onset at 8-11 Years of Age: Watershed Ages When Syndromes Overlap.8-11 岁起病的隐源性癫痫的转归:综合征重叠的关键年龄。
J Child Neurol. 2023 Aug;38(8-9):505-512. doi: 10.1177/08830738231188397. Epub 2023 Jul 17.
2
A Practical Guide to Treatment of Childhood Absence Epilepsy.儿童失神癫痫治疗实用指南。
Paediatr Drugs. 2019 Feb;21(1):15-24. doi: 10.1007/s40272-019-00325-x.
3
EEG correlates of seizure freedom in genetic generalized epilepsies.遗传性全身性癫痫发作缓解的脑电图相关性
Neurol Clin Pract. 2017 Feb;7(1):35-44. doi: 10.1212/CPJ.0000000000000323.
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Polyspike and waves do not predict generalized tonic-clonic seizures in childhood absence epilepsy.多棘慢波不能预测儿童失神癫痫的全面强直阵挛发作。
J Child Neurol. 2010 Apr;25(4):475-81. doi: 10.1177/0883073809341665.
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Therapeutic response of absence seizures in patients of an epilepsy clinic for adolescents and adults.青少年及成人癫痫门诊患者失神发作的治疗反应
J Neurol. 1984;231(4):225-9. doi: 10.1007/BF00313944.