Sato S, Dreifuss F E, Penry J K
Neurology. 1976 Aug;26(8):788-96. doi: 10.1212/wnl.26.8.788.
A prospective follow-up study was conducted on 48 epileptic patients (22 males and 26 females) who had participated in a collaborative study of absence seizures about 7 years earlier. Multivariate analysis showed that the significant prognostic factors for absence seizures were normal or above normal intelligence and normal electroencephalographic background activity. For any seizure type, significant prognostic factors were a negative history of generalized tonic-clonic seizures, normal or above normal intelligence, and a negative family history of seizure disorders. Nearly 90 percent of the patients with all significant prognostic factors for both absence seizures and seizures of all types ceased having seizures.
对约7年前参与失神发作协作研究的48例癫痫患者(22例男性和26例女性)进行了前瞻性随访研究。多变量分析显示,失神发作的显著预后因素为智力正常或高于正常以及脑电图背景活动正常。对于任何癫痫发作类型,显著预后因素为全身强直阵挛性发作阴性病史、智力正常或高于正常以及癫痫障碍家族史阴性。具有失神发作和所有类型癫痫发作的所有显著预后因素的患者中,近90%停止发作。