Sato S, Dreifuss F E, Penry J K, Kirby D D, Palesch Y
Neurology. 1983 Dec;33(12):1590-5. doi: 10.1212/wnl.33.12.1590.
The prognosis of absence seizures was evaluated in 83 patients by univariate and multivariate analysis. The mean follow-up period was 9.5 years. Normal intelligence quotient (IQ) was found to be a significant prognostic factor by both methods of analysis, but multivariate analysis showed that normal IQ, no hyperventilation-induced spikes and waves, male sex, and normal neurologic findings were significant prognostic factors associated with cessation of all types of seizures. More than 90% of patients with three or more significant factors stopped having seizures. A multiple logistic regression model describes the population and can be used for estimating the outcome of patients with absence seizures.
通过单因素和多因素分析对83例失神发作患者的预后进行了评估。平均随访期为9.5年。两种分析方法均发现正常智商（IQ）是一个重要的预后因素，但多因素分析表明，正常智商、无过度换气诱发的棘波和慢波、男性以及正常神经系统检查结果是与所有类型癫痫发作停止相关的重要预后因素。有三个或更多重要因素的患者中，超过90%停止了癫痫发作。一个多元逻辑回归模型描述了该人群，可用于估计失神发作患者的预后。
