García-Castiñeiras S, Andino Moreno M E, Pérez R, Vázquez L A
Department of Ophthalmology, School of Medicine, University of Puerto Rico, San Juan 00936-5067.
P R Health Sci J. 1993 Jun;12(2):123-8.
Levels of serum antibodies against lens alpha, beta H and beta L crystallins were determined in 15 patients before and after endocapsular cataract extraction. The most abundant antibody at the time of surgery was anti-beta L, followed by anti-beta H and anti-alpha. An increase in the basal levels of these antibodies was seen after surgery in 93 percent of the cases. Relative increase was highest for anti-alpha, followed by anti-beta H and anti-beta L. There were individual variations both in the shape of the time-dependent antibody response after surgery and in the relative intensity of the response to the different antigens. The endocapsular technique therefore leads to the release of crystallins into the anterior chamber in sufficient amounts to provoke in many patients a humoral immune response.
测定了15例囊内白内障摘除术前、后的血清中抗晶状体α、βH和βL晶状体蛋白抗体水平。手术时最丰富的抗体是抗βL，其次是抗βH和抗α。93%的病例术后这些抗体的基础水平有所升高。抗α的相对升高最高，其次是抗βH和抗βL。术后抗体反应随时间变化的形状以及对不同抗原反应的相对强度均存在个体差异。因此，囊内技术导致足够量的晶状体蛋白释放到前房，从而在许多患者中引发体液免疫反应。
