Majluf-Cruz A S, Marín-López A, Luis A
Departamento de Hematología, Instituto Nacional de la Nutrición Salvador, Zubirán, México, D.F.
Sangre (Barc). 1993 Jun;38(3):207-10.
To analyse the results of a pre-deposit autologous transfusion programme in pregnant women on their third period of pregnancy.
Fifty donor/pregnant women were included in the study. They were in the third trimester of their pregnancy and had risk of requiring transfusion during or after surgery. Haemoglobin above 11 g/dL and haematocrit above 34% were required in each case. Phlebotomy was performed at one-week intervals, iron and folate being supplied. Constants such as foetal heart frequency were evaluated, the programme being interrupted in case of foetal bradycardia. Apart from weight, Apgar and Silverman scores were applied to each newborn.
Cephalopelvic disproportion was the commonest obstetric indication, 26 cases (52%). For autologous blood transfusion, rare blood groups, 12 cases (24%), followed by intra- or post-operative bleeding risk, 10 cases (20%) and being Jehovah's Witnesses, 9 cases (18%), were the major indications. Ninety-four blood units were drawn, 34 of them being used. The remaining 60 units were used for homologous transfusion. No complications developed during phlebotomy and the neonatal determinations showed no significant anomalies.
(1) Autologous blood transfusion with pre-deposit in the third trimester of pregnancy is a safe and effective way of collecting blood. (2) Its indication is not reduced to rare blood groups. (3) The procedure seems to be safe for both the mother and the newborn.
分析孕晚期孕妇预存式自体输血方案的结果。
50名献血孕妇纳入本研究。她们处于妊娠晚期,手术期间或术后有输血风险。要求每位孕妇血红蛋白高于11g/dL,血细胞比容高于34%。每隔一周进行一次采血,并补充铁和叶酸。评估诸如胎儿心率等常量,若出现胎儿心动过缓则中断该方案。除体重外,对每个新生儿应用阿氏评分和西尔弗曼评分。
头盆不称是最常见的产科指征,26例(52%)。自体输血的主要指征依次为稀有血型,12例(24%);其次是术中和术后出血风险,10例(20%);以及耶和华见证会信徒,9例(18%)。共采集94个血单位,其中34个被使用。其余60个血单位用于异体输血。采血过程中未出现并发症,新生儿检测未显示明显异常。
(1)孕晚期预存式自体输血是一种安全有效的采血方式。(2)其适应证不限于稀有血型。(3)该程序对母亲和新生儿似乎都是安全的。