Alonso P L, Lindsay S W, Armstrong Schellenberg J R, Gomez P, Hill A G, David P H, Fegan G, Cham K, Greenwood B M
Medical Research Council Laboratories, Fajara, Banjul, The Gambia.
Trans R Soc Trop Med Hyg. 1993 Jun;87 Suppl 2:13-7. doi: 10.1016/0035-9203(93)90170-u.
Background data on child mortality and morbidity from malaria were obtained in a new study area in the centre of The Gambia, south of the river, chosen as the site for a malaria intervention trial. Infant and child mortality rates were 120 and 41 per 1000 respectively. Results obtained using post-mortem questionnaires suggested that malaria was an uncommon cause of death in children under the age of one year but responsible for about 40% of deaths in children aged 1-4 years. Ninety-two percent of deaths attributed to malaria occurred during or immediately after the rainy season. Parasite and spleen rates in children aged 1-5 years at the end of the malaria transmission season were 66% and 64% respectively. Malariometric indices were similar in primary health care (PHC) villages, selected as sites for an intervention with insecticide-treated bed nets and targeted chemoprophylaxis, and in smaller, non-PHC, control villages.
在冈比亚中部、河流以南一个新的研究区域获取了有关疟疾导致儿童死亡率和发病率的背景数据，该区域被选为疟疾干预试验地点。婴儿和儿童死亡率分别为每1000人中有120人和41人。使用尸检问卷得出的结果表明，疟疾在一岁以下儿童中并非常见死因，但在1至4岁儿童死亡中约占40%。归因于疟疾的死亡中有92%发生在雨季期间或雨季刚结束时。疟疾传播季节结束时，1至5岁儿童的寄生虫感染率和脾脏肿大率分别为66%和64%。在被选为使用经杀虫剂处理的蚊帐和有针对性的化学预防措施进行干预地点的初级卫生保健（PHC）村庄，以及较小的非初级卫生保健对照村庄，疟疾指标相似。
