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在西非冈比亚农村地区开展的一项使用经杀虫剂处理的蚊帐和针对性化学预防措施的疟疾控制试验。8. 仅使用蚊帐浸渍或与化学预防措施相结合在预防冈比亚儿童疟疾死亡率和发病率方面的成本效益。

A malaria control trial using insecticide-treated bed nets and targeted chemoprophylaxis in a rural area of The Gambia, west Africa. 8. Cost-effectiveness of bed net impregnation alone or combined with chemoprophylaxis in preventing mortality and morbidity from malaria in Gambian children.

作者信息

Picard J, Aikins M, Alonso P L, Armstrong Schellenberg J R, Greenwood B M, Mills A

机构信息

London School of Hygiene and Tropical Medicine, UK.

出版信息

Trans R Soc Trop Med Hyg. 1993 Jun;87 Suppl 2:53-7. doi: 10.1016/0035-9203(93)90176-q.

Abstract

In The Gambia, insecticide impregnation of bed nets, used alone or combined with Maloprim, reduced morbidity and mortality from malaria amongst children between one and 4 years of age. Taking expenditure of both time and money by public authorities and village volunteers into account, the costs and cost-effectiveness of each intervention were estimated. Bed net impregnation alone and the combined strategy cost US $5.65 and US $7.49 per child-year protected respectively (1990 figures). Insecticide (and drugs) accounted for more than 80% of the costs of each intervention strategy. They were both highly cost-effective. Estimated costs per death and per clinical episode of malaria averted were US $188 and US $28 for bed net impregnation and $257 and $19 for impregnation combined with chemoprophylaxis. Estimated costs per healthy year of life saved, discounted at 3%, were US $7.90 and US $10.84.

摘要

在冈比亚,单独使用或与氨酚喹联合使用的经杀虫剂处理的蚊帐,降低了1至4岁儿童疟疾的发病率和死亡率。考虑到公共当局和乡村志愿者投入的时间和资金,对每种干预措施的成本及成本效益进行了估算。仅蚊帐处理和联合策略分别为每个受保护儿童年花费5.65美元和7.49美元(1990年数据)。杀虫剂(和药物)占每种干预策略成本的80%以上。两种策略都具有很高的成本效益。经杀虫剂处理蚊帐预防每例死亡和每例疟疾临床发作的估计成本分别为188美元和28美元,与化学预防联合处理蚊帐的成本则分别为257美元和19美元。按3%贴现率计算,每挽救一个健康生命年的估计成本分别为7.90美元和10.84美元。

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