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[卵子捐赠。丹麦公立生育诊所治疗统一指南的综述与建议]

[Ovum donation. A review of and a suggestion to unified guidelines for treatment at public fertility clinics in Denmark].

作者信息

Andersen A N, Larsen J F, Hornnes P J, Starup J, Andersen C Y, Westergaard L G, Rasmussen P E, Ingerslev H J, Maigaard S

机构信息

Gynaekologisk-obstetrisk afdeling, Københavns Amts Sygehus i Herlev.

出版信息

Ugeskr Laeger. 1993 Aug 16;155(33):2515-9.

PMID:8212352
Abstract

The most common indication for oocyte donation is ovarian insufficiency due to premature menopause or resistant ovarian syndrome and ovarian dysgenesis with either normal or abnormal (e.g. Turner's syndrome) karyotype. In Denmark, oocyte donation must be anonymous, and the donors have to be other infertile patients undergoing in vitro fertilisation (IVF), treatment. It is suggested, that the National Health Service offers oocyte donation to hypergonadotropic women with ovarian insufficiency, as well as to a few other groups who fulfil the criteria for IVF treatment, but where this treatment cannot be completed. Oocyte donors must be less than 35 years old, physically and mentally healthy and without major genetic diseases in the family. The donor must be screened for HIV, hepatitis, syphilis, chlamydia and gonorrhoea. We propose that those patients who have more than six oocytes aspirated, allowing "surplus" oocytes to be donated. It is also proposed that the departmental order from the Ministry of Health be changed, so that normally fertile women are allowed to donate oocytes. Oocyte donation should be reported to a central authority.

摘要

卵子捐赠最常见的指征是由于过早绝经或卵巢抵抗综合征导致的卵巢功能不全,以及核型正常或异常(如特纳综合征)的卵巢发育不全。在丹麦,卵子捐赠必须是匿名的,捐赠者必须是其他正在接受体外受精(IVF)治疗的不孕患者。建议国家医疗服务体系为促性腺激素水平高且卵巢功能不全的女性,以及其他一些符合IVF治疗标准但无法完成该治疗的群体提供卵子捐赠。卵子捐赠者必须年龄小于35岁,身心健康,且家族中无重大遗传疾病。必须对捐赠者进行艾滋病毒、肝炎、梅毒、衣原体和淋病筛查。我们建议那些吸出超过六个卵子的患者,允许捐赠“多余”的卵子。还建议更改卫生部的部门命令,以便允许正常可育女性捐赠卵子。卵子捐赠应上报给中央机构。

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