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[生产活炭疽疫苗中种子材料的标准化]

[Standardization of the seeding material in producing live anthrax vaccine].

作者信息

Gladus M A, Nikolaenko Iu P, Lazareva E S, Fatkhinurova T I, Mashilova G M

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1978 Sep(9):42-6.

PMID:106609
Abstract

Technology of obtaining dry concentrated seeding material of the anthrax bacillus STI-1 vaccine strain was worked out. The use of dry seeding material for making dry anthrax vaccine rendered the preparations obtained more standard, reduced the time required for their production, led to increase of AKM-SH productivity, and to greater profitability of the vaccine production. The vaccine preparations obtained with the use of dry seeding material did not differ from control by immunogenicity.

摘要

已研发出获取炭疽杆菌STI - 1疫苗株干燥浓缩接种材料的技术。使用干燥接种材料制备干燥炭疽疫苗,使所获制剂更具标准性,缩短了生产所需时间,提高了AKM - SH的生产率,并提升了疫苗生产的盈利能力。使用干燥接种材料获得的疫苗制剂在免疫原性方面与对照无异。

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