Synthesis of L-carnitine by microorganisms and isolated enzymes.

L-Carnitine, a quaternary ammonium compound, plays an important role in beta-oxidation of fatty acids in mammals. The increasing demand for this compound in medicine has led to the development of numerous procedures for L-carnitine production. This review discusses the possibilities of microbial and enzymatical synthesis of L-carnitine and gives an overview on the pathways of L-carnitine metabolism and related enzymes in microorganisms.