Fedder J, Askjaer S A, Hjort T
Department of Surgery and Obstetrics, Skive Hospital, Denmark.
Arch Androl. 1993 Sep-Oct;31(2):95-103. doi: 10.3109/01485019308988386.
In semen samples from 94 men from infertile couples and 42 control patients proven to be fertile the occurrence of different kinds of nonspermatozoal cells (NSC) was examined. The findings were evaluated in relation to other seminal parameters and to the fertility status of the couple. The ratios of NSC to sperm and primary spermatocytes to spermatids revealed increasing values with decreasing sperm counts. Especially in a group where the semen samples contained > or = 6 x 10(6) motile sperm per mL and no infertility factor was detectable in the woman, the concentration of leukocytes was high, with three of eight patients having > or = 10(6) leukocytes per mL. A high proportion of abnormal sperm seemed to occur more frequently where the cause of infertility could be found in the man. A high number of leukocytes was neither significantly associated to an increased proportion of abnormal sperm nor to sperm motility evaluated by recording the percentage of motile sperm and the 1-h migration distance in sodium hyaluronate medium. No correlation between concentration of lymphocytes and presence of antisperm antibodies in seminal plasma was detectable.
对94例不育夫妇男性的精液样本以及42例已证实具有生育能力的对照患者的精液样本进行了检查，以确定不同种类非精子细胞（NSC）的出现情况。研究结果与其他精液参数以及夫妇的生育状况相关联进行评估。NSC与精子的比例以及初级精母细胞与精子细胞的比例显示，随着精子数量的减少而增加。特别是在精液样本每毫升含有≥6×10⁶条活动精子且女性未检测到不孕因素的一组中，白细胞浓度较高，8例患者中有3例每毫升白细胞≥10⁶。在男性存在不孕原因的情况下，似乎异常精子的高比例出现得更为频繁。通过记录透明质酸钠培养基中活动精子的百分比和1小时迁移距离来评估，白细胞数量高与异常精子比例增加或精子活力均无显著关联。精液中淋巴细胞浓度与抗精子抗体的存在之间未检测到相关性。
