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左冠状动脉主干疾病:早期手术结果及其与颈动脉狭窄的关联。

Disease of the left main coronary artery: early surgical results and their association with carotid artery stenosis.

作者信息

Vigneswaran W T, Sapsford R N, Stanbridge R D

机构信息

St Mary's Hospital, London.

出版信息

Br Heart J. 1993 Oct;70(4):342-5. doi: 10.1136/hrt.70.4.342.

Abstract

OBJECTIVES

To review the results of surgical revascularisation for left main coronary artery stenosis and the associated vascular pathology that is responsible for cerebrovascular complication.

PATIENTS

60 patients (45 men, 15 women) (mean age 61.3 (39-79)) who underwent revascularisation for stenosis of the left main stem coronary artery (LMS) between January 1987 and August 1990 were compared with an age and sex matched control group of patients undergoing revascularisation for triple vessel disease during the same period.

OUTCOME MEASURES

In-hospital morbidity and operative mortality.

RESULTS

24 patients in the LMS group presented with unstable angina. The left ventricular ejection fraction was less than 50% in 30 patients and less than 30% in nine. 17 patients (28%) had large vessel extracranial carotid artery disease and 10 patients had vascular disease of the lower limbs. In six patients atheromatous plaques were noted in the ascending aorta during surgery. There was no in-hospital mortality. In-hospital morbidity included neurological deficits in five (8.3%), arrhythmias in seven (11.6%), and pulmonary complications in six (10%) patients. The incidence of carotid artery disease in the LMS group was significantly higher (p = 0.04). Atheromatous plaque in the ascending aorta and postoperative neurological complications were more common patients with LMS.

CONCLUSIONS

The incidence of carotid artery disease was higher and postoperative cerebrovascular complications were more common in patients who had coronary artery revascularisation for stenosis of the left main stem coronary artery. The early surgical results were excellent. These findings suggest that for optimum perioperative management patients with stenosis of the left main coronary artery should be screened for carotid artery disease before bypass surgery.

摘要

目的

回顾左主干冠状动脉狭窄的外科血管重建结果以及导致脑血管并发症的相关血管病变。

患者

将1987年1月至1990年8月间因左主干冠状动脉(LMS)狭窄接受血管重建的60例患者(45例男性,15例女性)(平均年龄61.3岁(39 - 79岁))与同期因三支血管病变接受血管重建的年龄和性别匹配的对照组患者进行比较。

观察指标

住院发病率和手术死亡率。

结果

LMS组中有24例患者表现为不稳定型心绞痛。30例患者的左心室射血分数低于50%,9例低于30%。17例患者(28%)患有颅外大血管颈动脉疾病,10例患者患有下肢血管疾病。6例患者在手术过程中发现升主动脉有动脉粥样硬化斑块。无住院死亡病例。住院发病率包括5例(8.3%)出现神经功能缺损、7例(11.6%)出现心律失常以及6例(10%)出现肺部并发症。LMS组中颈动脉疾病的发生率显著更高(p = 0.04)。升主动脉动脉粥样硬化斑块和术后神经并发症在LMS患者中更为常见。

结论

因左主干冠状动脉狭窄接受冠状动脉血管重建的患者中,颈动脉疾病的发生率更高,术后脑血管并发症更常见。早期手术结果良好。这些发现表明,为实现最佳围手术期管理,左主干冠状动脉狭窄患者在搭桥手术前应筛查颈动脉疾病。

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