绒毛膜绒毛的体视显微镜显示：流产与异位妊娠的鉴别

Stereomicroscopic demonstration of chorionic villi: differentiation between miscarriage and ectopic pregnancy.

作者信息

Kristiansen J D, Clausen I, Nielsen M N, Thomsen S G

机构信息

Department of Obstetrics and Gynecology, Odense University Hospital, Denmark.

出版信息

Br J Obstet Gynaecol. 1993 Sep;100(9):839-41. doi: 10.1111/j.1471-0528.1993.tb14310.x.

DOI:10.1111/j.1471-0528.1993.tb14310.x

PMID:8218005

Abstract

OBJECTIVE

To evaluate direct peroperative stereomicroscopic examination of endometrial curettings in the differentiation between miscarriage and ectopic pregnancy.

DESIGN

A prospective consecutive controlled study.

SETTING

Odense University Hospital, Odense, Denmark.

SUBJECTS

One hundred and fifty-nine women with vaginal bleeding and/or abdominal pain in early pregnancy and no fetus seen on ultrasound.

MAIN OUTCOME MEASURES

The results of stereomicroscopy were compared with the histological diagnoses.

RESULTS

There was 90% (95% CI, 84-94%) agreement between the stereomicroscopic and histological examinations. Fifteen per cent had an ectopic pregnancy. The sensitivity of stereomicroscopy as a marker of ectopic pregnancy was 92% (73-99%), the specificity 94% (88-97%). The predictive value of a positive test was 73% (54-88%) and that of a negative test 98% (94-100%).

CONCLUSION

Direct peroperative stereomicroscopy of endometrial curettings is a valuable diagnostic tool for immediate differentiation between miscarriage and ectopic pregnancy.

摘要

目的

评估术中直接对子宫内膜刮出物进行体视显微镜检查在鉴别流产与异位妊娠中的作用。

设计

一项前瞻性连续对照研究。

地点

丹麦欧登塞市欧登塞大学医院。

研究对象

159例孕早期出现阴道流血和/或腹痛且超声检查未见胎儿的女性。

主要观察指标

将体视显微镜检查结果与组织学诊断结果进行比较。

结果

体视显微镜检查与组织学检查结果的一致性为90%（95%可信区间，84 - 94%）。15%的患者为异位妊娠。体视显微镜检查作为异位妊娠标志物的敏感性为92%（73 - 99%），特异性为94%（88 - 97%）。阳性试验的预测值为73%（54 - 88%），阴性试验的预测值为98%（94 - 100%）。