Mermoud A, Salmon J F, Straker C, Murray A D
Department of Ophthalmology, Groote Schuur Hospital, South Africa.
Br J Ophthalmol. 1993 Oct;77(10):631-4. doi: 10.1136/bjo.77.10.631.
In order to determine if post-traumatic angle recession is a risk factor for failure of glaucoma filtering surgery independent of age or race, the surgical results of trabeculectomy performed in 35 consecutive patients with angle recession glaucoma were compared with those of 35 matched patients with primary open angle glaucoma. A postoperative intraocular pressure of < or = 21 mm Hg (with or without glaucoma medication) was found in 15 of the 35 (43%) patients with angle recession glaucoma compared with 26 of the 35 (74%) patients with primary open angle glaucoma. The long term success of trabeculectomy was significantly worse in angle recession glaucoma when the results were analysed using Kaplan-Meier survival curves. Bleb failure occurred a mean period of 3.1 (SD 1.2) months after trabeculectomy in angle recession glaucoma compared with 9.4 (5) months in primary open angle glaucoma (p < or = 0.001). The finding that posttraumatic angle recession is a risk factor for failure of trabeculectomy, supports the use of antimetabolite therapy to suppress fibrosis after trabeculectomy in these patients.
为了确定创伤后房角后退是否是青光眼滤过手术失败的危险因素,且独立于年龄或种族因素,将35例连续性房角后退性青光眼患者小梁切除术的手术结果与35例匹配的原发性开角型青光眼患者的手术结果进行比较。35例房角后退性青光眼患者中有15例(43%)术后眼压≤21 mmHg(使用或未使用青光眼药物),而35例原发性开角型青光眼患者中有26例(74%)达到此眼压水平。当使用Kaplan-Meier生存曲线分析结果时,房角后退性青光眼小梁切除术的长期成功率明显更低。房角后退性青光眼小梁切除术后滤过泡失败的平均时间为3.1(标准差1.2)个月,而原发性开角型青光眼为9.4(5)个月(p≤0.001)。创伤后房角后退是小梁切除术失败的危险因素这一发现,支持在这些患者的小梁切除术后使用抗代谢药物治疗以抑制纤维化。