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Mutant of Pseudomonas aeruginosa 18S that synthesizes type Id beta-lactamase constitutively.铜绿假单胞菌18S的突变体，该突变体组成型合成I型β-内酰胺酶。
J Bacteriol. 1976 Sep;127(3):1585-6. doi: 10.1128/jb.127.3.1585-1586.1976.
2
R factors, beta-lactamase, and carbenicillin-resistant Pseudomonas aeruginosa.R因子、β-内酰胺酶与耐羧苄青霉素的铜绿假单胞菌
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3
[Effect of the induction of beta-lactamase synthesis in Pseudomonas aeruginosa strains on their resistance to penicillin].[铜绿假单胞菌菌株中β-内酰胺酶合成诱导对其青霉素耐药性的影响]
Antibiotiki. 1975 Jan;20(1):59-62.
4
[Relationship between beta-lactamase activity of clinical strains of Pseudomonas pyocyanea and their resistance to penicillins].[绿脓杆菌临床菌株的β-内酰胺酶活性与其对青霉素耐药性之间的关系]
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The control of class I beta-lactamase expression in Enterobacteriaceae and Pseudomonas aeruginosa.肠杆菌科细菌和铜绿假单胞菌中I类β-内酰胺酶表达的调控
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6
Induction kinetics of beta-lactamase biosynthesis in Pseudomonas aeruginosa.铜绿假单胞菌中β-内酰胺酶生物合成的诱导动力学
Antimicrob Agents Chemother. 1974 Dec;6(6):734-40. doi: 10.1128/AAC.6.6.734.
7
Mutants of Pseudomonas aeruginosa with impaired -lactamase inducibility and increased sensitivity to -lactam antibiotics.铜绿假单胞菌突变体，其β-内酰胺酶诱导性受损且对β-内酰胺抗生素敏感性增加。
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Heterogeneity of class I beta-lactamase expression in clinical isolates of Pseudomonas aeruginosa.铜绿假单胞菌临床分离株中I类β-内酰胺酶表达的异质性
Antimicrob Agents Chemother. 1988 Dec;32(12):1893-5. doi: 10.1128/AAC.32.12.1893.
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The presence of a variant of type-IIIa beta-lactamase in a series of strains isolated in a burns unit.
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Carbenicillin as inhibitor of beta-lactamase from Pseudomonas aeruginosa.羧苄青霉素作为铜绿假单胞菌β-内酰胺酶的抑制剂。
Nat New Biol. 1972 Jan 26;235(56):121-2. doi: 10.1038/newbio235121a0.

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Exploring sequence requirements for C₃/C₄ carboxylate recognition in the Pseudomonas aeruginosa cephalosporinase: Insights into plasticity of the AmpC β-lactamase.探索铜绿假单胞菌头孢菌素酶中 C₃/C₄ 羧酸盐识别的序列要求：对 AmpC β-内酰胺酶可塑性的深入了解。
Protein Sci. 2011 Jun;20(6):941-58. doi: 10.1002/pro.612. Epub 2011 May 3.
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The acyl-enzyme mechanism of beta-lactamase action. The evidence for class C Beta-lactamases.β-内酰胺酶作用的酰基-酶机制。C类β-内酰胺酶的证据。
Biochem J. 1982 Nov 1;207(2):315-22. doi: 10.1042/bj2070315.
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Biochem J. 1982 Mar 1;201(3):621-7. doi: 10.1042/bj2010621.
4
Selection of variants of Pseudomonas aeruginosa resistant of Beta-lactam antibiotics.耐β-内酰胺类抗生素铜绿假单胞菌变体的筛选
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Carboxy groups as essential residues in beta-lactamases.羧基作为β-内酰胺酶中的必需残基。
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本文引用的文献

1
Staphylococcal penicillinase and the new penicillins.葡萄球菌青霉素酶与新型青霉素
Biochem J. 1962 May;83(2):229-35. doi: 10.1042/bj0830229.
2
HIGH PENICILLINASE PRODUCTION CORRELATED WITH MULTIPLE ANTIBIOTIC RESISTANCE IN STAPHYLOCOCCUS AUREUS.金黄色葡萄球菌中青霉素酶的高产量与多重抗生素耐药性相关。
Lancet. 1964 Feb 8;1(7328):293-6. doi: 10.1016/s0140-6736(64)92407-9.
3
ANALYSIS BY TRANSDUCTION OF MUTATIONS AFFECTING PENICILLINASE FORMATION IN STAPHYLOCOCCUS AUREUS.通过转导分析影响金黄色葡萄球菌青霉素酶形成的突变
J Gen Microbiol. 1963 Oct;33:121-36. doi: 10.1099/00221287-33-1-121.
4
PRODUCTION OF A CEPHALOSPORINASE BY PSEUDOMONAS PYOCYANEA.铜绿假单胞菌产生头孢菌素酶。
Nature. 1963 Jul 27;199:375. doi: 10.1038/199375a0.
5
Purification of penicillin-induced penicillinase of Bacillus cereus NRRL 569: a comparison of its properties with those of a similarly purified penicillinase produced spontaneously by a constitutive mutant strain.蜡样芽孢杆菌NRRL 569青霉素诱导型青霉素酶的纯化：将其特性与组成型突变株自发产生的类似纯化青霉素酶的特性进行比较。
Biochem J. 1956 Mar;62(3):391-401. doi: 10.1042/bj0620391.
6
Cephalosporinase and penicillinase activities of a beta-lactamase from Pseudomonas pyocyanea.铜绿假单胞菌β-内酰胺酶的头孢菌素酶和青霉素酶活性
Biochem J. 1965 Sep;96(3):739-52. doi: 10.1042/bj0960739.
7
A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria.对革兰氏阴性菌合成的八种不同β-内酰胺酶的比较研究。
J Gen Microbiol. 1970 Apr;61(1):43-61. doi: 10.1099/00221287-61-1-43.
8
The biochemistry and function of beta-lactamase (penicillinase).β-内酰胺酶（青霉素酶）的生物化学与功能
Adv Enzymol Relat Areas Mol Biol. 1966;28:237-323. doi: 10.1002/9780470122730.ch4.
9
Mechanisms of drug resistance. The beta-lactamases of gram-negative bacteria including pseudomonads.耐药机制。革兰氏阴性菌（包括假单胞菌）的β-内酰胺酶。
Ann N Y Acad Sci. 1971 Jun 11;182:243-57. doi: 10.1111/j.1749-6632.1971.tb30661.x.
10
The surface localization of penicillinases in Escherichia coli and Salmonella typhimurium.青霉素酶在大肠杆菌和鼠伤寒沙门氏菌中的表面定位
Biochem Biophys Res Commun. 1968 Jul 26;32(2):258-63. doi: 10.1016/0006-291x(68)90378-1.

铜绿假单胞菌18S的突变体，该突变体组成型合成I型β-内酰胺酶。

Mutant of Pseudomonas aeruginosa 18S that synthesizes type Id beta-lactamase constitutively.

作者信息

Flett F, Curtis N A, Richmond M H

出版信息

J Bacteriol. 1976 Sep;127(3):1585-6. doi: 10.1128/jb.127.3.1585-1586.1976.

DOI:10.1128/jb.127.3.1585-1586.1976
PMID:821939
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC232961/
Abstract

A mutant of Pseudomonas aeruginosa 18S that constitutively synthesizes type Id beta-lactamase was isolated and some of its properties were elucidated.

摘要

分离出了铜绿假单胞菌18S的一个组成型合成I型β-内酰胺酶的突变体，并阐明了其一些特性。