细菌对聚维酮碘无耐药性。
Absence of bacterial resistance to povidone iodine.
作者信息
Houang E T, Gilmore O J, Reid C, Shaw E J
出版信息
J Clin Pathol. 1976 Aug;29(8):752-5. doi: 10.1136/jcp.29.8.752.
Abstract
Povidone iodine is now being increasingly used in hospitals as an antiseptic. The possible habituation of bacteria to iodine was studied by serial passage of two strains of Pseudomonas aeruginosa, two strains of Escherichia coli, two strains of Klebsiella aerogenes, and one strain of Serratia marcescens in subinhibitory concentrations. After 20 passages, no significant change was observed in the minimal inhibitory concentration, minimal bactericidal concentration, and killing times between parent strains and 20th subcultures under standardized conditions.
摘要
聚维酮碘作为一种消毒剂目前在医院中越来越多地被使用。通过将两株铜绿假单胞菌、两株大肠杆菌、两株产气克雷伯菌和一株粘质沙雷氏菌在亚抑菌浓度下连续传代，研究了细菌对碘可能产生的适应性。经过20代传代后，在标准化条件下，亲代菌株与第20代传代培养物之间的最低抑菌浓度、最低杀菌浓度和杀菌时间均未观察到显著变化。
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