Dixon L K, Baylis S A, Vydelingum S, Twigg S R, Hammond J M, Hingamp P M, Bristow C, Wilkinson P J, Smith G L
AFRC Institute for Animal Health, Pirbright, Woking, U.K.
Arch Virol Suppl. 1993;7:185-99. doi: 10.1007/978-3-7091-9300-6_15.
A 55 kilobase pair (kb) region from the right end of the virulent African swine fever virus isolate, Malawi LIL20/1, has been sequenced. The 68 major open reading frames (ORFs) encoded are generally closely spaced and read from both DNA strands across the complete sequence. Comparison of the amino acid sequences of predicted ORFs with sequence databases identified 15 ORFs which encode proteins that are similar to proteins of known function. Two ORFs are homologous to copies of multigene family 360 (MGF360) and one ORF is homologous to copies of multigene family 110 (MGF110). Both of these multigene families have been described previously.
来自强毒力非洲猪瘟病毒分离株马拉维LIL20/1右端的一段55千碱基对(kb)区域已完成测序。所编码的68个主要开放阅读框(ORF)通常间隔紧密,并且在整个序列中从两条DNA链上读取。将预测的ORF氨基酸序列与序列数据库进行比较,鉴定出15个ORF,它们编码的蛋白质与已知功能的蛋白质相似。两个ORF与多基因家族360(MGF360)的拷贝同源,一个ORF与多基因家族110(MGF110)的拷贝同源。这两个多基因家族此前均有描述。