激素替代疗法。风险、益处及成本。
Hormone replacement therapy. Risks, benefits, and costs.
作者信息
Delva M D
机构信息
Department of Family Medicine, Queen's University, Kingston, Ont.
出版信息
Can Fam Physician. 1993 Oct;39:2149-54.
Abstract
Epidemiologic evidence on the risks and benefits of hormone replacement therapy (HRT) for postmenopausal women is accumulating. The apparent 50% reduction in risk of cardiovascular mortality could lead to universal HRT. Until a prospective, controlled trial is concluded, women must consider all the consequences of HRT. For the undecided, who would take HRT only to prevent osteoporosis, bone mass estimates might be warranted.
摘要
关于激素替代疗法（HRT）对绝经后女性风险和益处的流行病学证据正在不断积累。心血管疾病死亡率明显降低50%，这可能会导致HRT的广泛应用。在一项前瞻性对照试验得出结论之前，女性必须考虑HRT的所有后果。对于那些犹豫不决、仅为预防骨质疏松症才会考虑使用HRT的女性而言，或许有必要进行骨量评估。
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