Beljanski M, Da Cunha M I
Mol Biol Rep. 1976 Jul;2(6):497-506. doi: 10.1007/BF00356939.
Particular RNA fragments obtained by action of pancreatic ribonuclease on purified RNAs originating from species totally unrelated to Agrobacterium tumefaciens (Escherichia coli, rabbit, monkey) are capable of inducing the formation of transplantable tumorous tissue when introduced at wounded sites in inverted stems of Datura stramonium maintained under axenic conditions on a medium containing auxin and kinetin. Reovirus RNA and a small size RNA (5-6S) isolated from RNA bound RNA directed DNA polymerase from Escherichia coli also induced the appearance of tumorous tissues which grow on solid synthetic medium in the absence of auxin and kinetin.
通过胰核糖核酸酶作用于源自与根癌土壤杆菌完全无关的物种（大肠杆菌、兔子、猴子）的纯化RNA所获得的特定RNA片段，当将其引入在含有生长素和激动素的培养基上无菌条件下培养的曼陀罗倒置茎的伤口部位时，能够诱导可移植肿瘤组织的形成。呼肠孤病毒RNA以及从大肠杆菌的RNA结合RNA指导的DNA聚合酶中分离出的小尺寸RNA（5 - 6S）也诱导了肿瘤组织的出现，这些肿瘤组织在没有生长素和激动素的固体合成培养基上生长。
