Biliary metabolites of 2,5,2',5'-tetrachlorobiphenyl in the rat.
作者信息
Norback D H, Seymour J L, Knieriem K M, Peterson R E, Allen J R
出版信息
Res Commun Chem Pathol Pharmacol. 1976 Jul;14(3):527-33.
PMID:822484
Abstract
Biliary metabolites of rats receiving 3H labeled 2,5,2',5'-tetrachlorobiphenyl, a component of commercial polychlorinated bipheyl (PCB) mixtures include 3-OH-2,5,2',5'-tetrachlorobiphenyl and a dihydrodiol tentatively identified as trans-3,4-dihydrodihydroxy-2,5,2',5'-tetrachlorobiphenyl. Metabolism of PCBs in the rat probably occurs in part through an arene oxide intermediate.
摘要
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