大肠杆菌K-12 DNA腺嘌呤甲基化酶（dam）突变体生存能力的遗传需求分析。
Analysis of the genetic requirements for viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants.
作者信息
Peterson K R, Mount D W
机构信息
Department of Molecular and Cellular Biology, University of Arizona, Tucson 85721.
出版信息
J Bacteriol. 1993 Nov;175(22):7505-8. doi: 10.1128/jb.175.22.7505-7508.1993.
Abstract
RecBCD protein, necessary for Escherichia coli dam mutant viability, is directly required for DNA repair. Recombination genes recF+, recN+, recO+, and recQ+ are not essential for dam mutant viability; they are required for recBC sbcBC dam mutant survival. mutH, mutL, or mutS mutations do not suppress subinduction of SOS genes in dam mutants.
摘要
RecBCD蛋白是大肠杆菌dam突变体存活所必需的，是DNA修复直接需要的。重组基因recF+、recN+、recO+和recQ+对dam突变体的存活不是必需的；它们是recBC sbcBC dam突变体存活所需要的。mutH、mutL或mutS突变不能抑制dam突变体中SOS基因的亚诱导。
相似文献
1
Analysis of the genetic requirements for viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants.
J Bacteriol. 1993 Nov;175(22):7505-8. doi: 10.1128/jb.175.22.7505-7508.1993.
2
Recombination is essential for viability of an Escherichia coli dam (DNA adenine methyltransferase) mutant.
J Bacteriol. 2000 Jan;182(2):463-8. doi: 10.1128/JB.182.2.463-468.2000.
3
Viability of Escherichia coli K-12 DNA adenine methylase (dam) mutants requires increased expression of specific genes in the SOS regulon.
Mol Gen Genet. 1985;201(1):14-9. doi: 10.1007/BF00397979.
4
Genetic analysis of double-strand break repair in Escherichia coli.
J Bacteriol. 1993 Aug;175(16):5176-85. doi: 10.1128/jb.175.16.5176-5185.1993.
5
RecJ nuclease is required for SOS induction after introduction of a double-strand break in a RecA loading deficient recB mutant of Escherichia coli.
Biochimie. 2008 Sep;90(9):1347-55. doi: 10.1016/j.biochi.2008.04.002. Epub 2008 Apr 10.
6
lon incompatibility associated with mutations causing SOS induction: null uvrD alleles induce an SOS response in Escherichia coli.
J Bacteriol. 2000 Jun;182(11):3151-7. doi: 10.1128/JB.182.11.3151-3157.2000.
7
Interspecies recombination and mismatch repair. Generation of mosaic genes and genomes.
Methods Mol Biol. 2000;152:149-57. doi: 10.1385/1-59259-068-3:149.
8
Repair of heteroduplex DNA molecules with multibase loops in Escherichia coli.
J Bacteriol. 1993 Jul;175(13):3972-80. doi: 10.1128/jb.175.13.3972-3980.1993.
9
sbcB sbcC null mutations allow RecF-mediated repair of arrested replication forks in rep recBC mutants.
Mol Microbiol. 1999 Aug;33(4):846-57. doi: 10.1046/j.1365-2958.1999.01532.x.
10
[Effect of neocarzinostatin on E. coli mutants deficient in DNA repair].
Z Naturforsch C J Biosci. 1989 Sep-Oct;44(9-10):791-6.
引用本文的文献
1
Synthesizing supercoiled circular DNA molecules in vitro.
Nucleic Acids Res. 2025 Sep 5;53(17). doi: 10.1093/nar/gkaf889.
2
Synthesizing unmodified, supercoiled circular DNA molecules .
bioRxiv. 2025 Jan 25:2025.01.24.634800. doi: 10.1101/2025.01.24.634800.
3
Antibiotic Toxicity Profiles of Strains Lacking DNA Methyltransferases.
ACS Omega. 2021 Mar 15;6(11):7834-7840. doi: 10.1021/acsomega.1c00378. eCollection 2021 Mar 23.
4
Conjoint expression and purification strategy for acquiring proteins with ultra-low DNA N6-methyladenine backgrounds in Escherichia coli.
Biosci Rep. 2021 Mar 26;41(3). doi: 10.1042/BSR20203769.
5
DNA Methylation.
EcoSal Plus. 2014 May;6(1). doi: 10.1128/ecosalplus.ESP-0003-2013.
6
Complete Genome Sequence of ER2796, a DNA Methyltransferase-Deficient Strain of Escherichia coli K-12.
PLoS One. 2015 May 26;10(5):e0127446. doi: 10.1371/journal.pone.0127446. eCollection 2015.
7
The SOS Regulatory Network.
EcoSal Plus. 2008 Jul 25;2008. doi: 10.1128/ecosalplus.5.4.3.
8
DNA adenine methyltransferase influences the virulence of Aeromonas hydrophila.
Infect Immun. 2006 Jan;74(1):410-24. doi: 10.1128/IAI.74.1.410-424.2006.
9
Generation of DNA-free Escherichia coli cells by 2-aminopurine requires mismatch repair and nonmethylated DNA.
J Bacteriol. 2006 Jan;188(1):339-42. doi: 10.1128/JB.188.1.339-342.2006.
10
Analysis of global gene expression and double-strand-break formation in DNA adenine methyltransferase- and mismatch repair-deficient Escherichia coli.
J Bacteriol. 2005 Oct;187(20):7027-37. doi: 10.1128/JB.187.20.7027-7037.2005.
本文引用的文献
1
Mutator mutations in Escherichia coli induced by the insertion of phage mu and the transposable resistance elements Tn5 and Tn10.
Mutat Res. 1982 Mar;93(1):25-33. doi: 10.1016/0027-5107(82)90122-1.
2
Isolation and characterization of Dam+ revertants and suppressor mutations that modify secondary phenotypes of dam-3 strains of Escherichia coli K-12.
Mol Gen Genet. 1980;178(2):309-15. doi: 10.1007/BF00270477.
3
Escherichia coli mutator mutants deficient in methylation-instructed DNA mismatch correction.
Proc Natl Acad Sci U S A. 1980 Feb;77(2):1063-7. doi: 10.1073/pnas.77.2.1063.
4
Induction of damage inducible (SOS) repair in dam mutants of Escherichia coli exposed to 2-aminopurine.
Mol Gen Genet. 1984;194(3):539-40. doi: 10.1007/BF00425572.
5
Correlation of DNA adenine methylase activity with spontaneous mutability in Escherichia coli K-12.
Gene. 1984 Apr;28(1):123-5. doi: 10.1016/0378-1119(84)90095-7.
6
Mutagenesis and inducible responses to deoxyribonucleic acid damage in Escherichia coli.
Microbiol Rev. 1984 Mar;48(1):60-93. doi: 10.1128/mr.48.1.60-93.1984.
7
Inducible expression of a gene specific to the RecF pathway for recombination in Escherichia coli K12.
Mol Gen Genet. 1983;190(1):162-7. doi: 10.1007/BF00330340.
8
Phenotypic reversal in dam mutants of Escherichia coli K-12 by a recombinant plasmid containing the dam+ gene.
J Bacteriol. 1983 Jan;153(1):562-5. doi: 10.1128/jb.153.1.562-565.1983.
9
Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli.
Mol Gen Genet. 1983;189(3):400-4. doi: 10.1007/BF00325901.
10
Mutants of Escherichia coli K12 which affect excision of transposon Tn10.
Basic Life Sci. 1982;20:245-58. doi: 10.1007/978-1-4613-3476-7_16.
Zotero 插件