Noda T, Kawada A, Hiruma M, Ishibashi A, Arai S
Department of Dermatology, National Defense Medical College, Saitama, Japan.
J Dermatol. 1993 Sep;20(9):540-4. doi: 10.1111/j.1346-8138.1993.tb01335.x.
The relationship among minimal erythema dose (MED), minimal delayed tanning dose (MDTD), and skin color was examined in 16 healthy volunteers using three different spectra. The subjects were exposed to UVB, UVA+B, and UV+Visible light (UV+Visible) with a xenon arc solar simulator as a light source. The MEDs for UVB and UVA+B were less than the MDTDs, whereas the MED for UV+Visible was higher than the MDTD. There was no significant correlation between the MED and the MDTD for UVB or UVA+B. The MED for UV+Visible was significantly correlated to the MDTD (p < 0.01). Skin color significantly correlated with MEDs for UVB and UVA+B (p < 0.01), but not for UV+Visible. There was no significant correlation between skin color and the MDTD for any spectra. From these results, it is suggested that the relationship between erythemal and melanogenic responses is dependent on spectral bands of the light source and that skin color is a predictor of UV-induced erythema.
使用三种不同光谱,对16名健康志愿者的最小红斑量(MED)、最小延迟晒黑量(MDTD)和肤色之间的关系进行了研究。以氙弧太阳模拟器作为光源,让受试者暴露于中波紫外线(UVB)、长波紫外线与中波紫外线(UVA+B)以及紫外线与可见光(UV+Visible)下。UVB和UVA+B的MED小于MDTD,而UV+Visible的MED高于MDTD。UVB或UVA+B的MED与MDTD之间无显著相关性。UV+Visible的MED与MDTD显著相关(p<0.01)。肤色与UVB和UVA+B的MED显著相关(p<0.01),但与UV+Visible的MED无关。肤色与任何光谱的MDTD之间均无显著相关性。从这些结果表明,红斑反应和黑素生成反应之间的关系取决于光源的光谱波段,并且肤色是紫外线诱导红斑的一个预测指标。