Leenutaphong V
Department of Dermatology, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Photodermatol Photoimmunol Photomed. 1995 Oct-Dec;11(5-6):198-203. doi: 10.1111/j.1600-0781.1995.tb00169.x.
Predictors of sensitivity to ultraviolet (UV) light, including Fitzpatrick's sun reactive skin types, constitutive skin color and facultative skin color were assessed in 43 healthy Thai volunteers. These predictors were compared with one another and with responses of the skin to UV irradiation, as determined by a minimal erythema dose (MED) of UVB, a minimal immediate pigment darkening dose (MIPDD) of UVA, and a minimal delayed tanning dose (MDTD) of UVA, and by dose-response curves for erythema and pigmentation, as measured objectively with the use of a narrow-band spectrophotometer. The skin type did not correspond well to the constitutive and facultative skin color. There was no correlation between skin type and MED and no relation between skin type and the slope of the dose-response curves for erythema and pigmentation. Constitutional skin color was also not a good predictor of the measured MED, MIPDD and MDTD values but did appear to correlate with the steepness of the dose-response curves for erythema but not for pigmentation. The facultative skin color, however, did not correlate with the dose-response angle of erythema or pigmentation. We have thus found that the skin type is not a good predictor of UV responses in Thai. The constitutive skin color is a better predictor of UV responses of the skin than skin type and that steepness of dose-response curves for erythema is a better measure of the response of the skin to UV irradiation than is a MED measurement.
在43名健康的泰国志愿者中评估了对紫外线（UV）敏感性的预测因素，包括菲茨帕特里克日光反应性皮肤类型、固有肤色和适应性肤色。将这些预测因素相互比较，并与皮肤对紫外线照射的反应进行比较，皮肤对紫外线照射的反应由UVB的最小红斑剂量（MED）、UVA的最小即时色素沉着剂量（MIPDD）和UVA的最小延迟晒黑剂量（MDTD）确定，以及通过使用窄带分光光度计客观测量的红斑和色素沉着的剂量反应曲线来确定。皮肤类型与固有肤色和适应性肤色的对应性不佳。皮肤类型与MED之间没有相关性，皮肤类型与红斑和色素沉着的剂量反应曲线斜率之间也没有关系。固有肤色也不是所测量的MED、MIPDD和MDTD值的良好预测指标，但似乎与红斑的剂量反应曲线的陡峭程度相关，而与色素沉着的剂量反应曲线陡峭程度无关。然而，适应性肤色与红斑或色素沉着的剂量反应角度无关。因此，我们发现皮肤类型不是泰国人紫外线反应的良好预测指标。固有肤色比皮肤类型更能预测皮肤的紫外线反应，并且红斑剂量反应曲线的陡峭程度比MED测量更能衡量皮肤对紫外线照射的反应。
