Otsen M, Den Bieman M, van Zutphen L F
Department of Laboratory Animal Science, University of Utrecht, The Netherlands.
J Hered. 1993 Mar-Apr;84(2):149-51. doi: 10.1093/oxfordjournals.jhered.a111303.
Genetic analysis of a (BN x ACI)ACI backcross for the biochemical markers Es-1 and Es-2 (linkage group V) and a microsatellite marker of Ucp (chromosome 19) revealed linkage between these three loci. This linkage relationship confirms that in the rat linkage group V genes are located on chromosome 19. Genetic analysis of a (BN x LEW)LEW backcross showed that Hp is linked to Ucp, thus indicating that the Hp locus is also located on chromosome 19. These results substantiate the linkage homology of RNO 19, MMU 8, and HSA 16.
对（BN×ACI）ACI回交群体进行与生化标记Es-1和Es-2（连锁群V）以及Ucp微卫星标记（19号染色体）相关的遗传分析，结果显示这三个基因座之间存在连锁关系。这种连锁关系证实，在大鼠中，连锁群V的基因位于19号染色体上。对（BN×LEW）LEW回交群体的遗传分析表明，Hp与Ucp连锁，因此表明Hp基因座也位于19号染色体上。这些结果证实了RNO 19、MMU 8和HSA 16之间的连锁同源性。
