Liu Y T, Sui M J, Ji D D, Wu I H, Chou C C, Chen C C
Department of Microbiology and Immunology, National Defense Medical Center, Taipei, Republic of China.
J Invertebr Pathol. 1993 Sep;62(2):131-6. doi: 10.1006/jipa.1993.1088.
A process for production, isolation, and purification of melanin produced by the fermentation of Streptomyces lividans 66 harboring a recombinant plasmid pIJ702-bearing tyrosinase gene has been developed. The efficacy of melanin in the protection of mosquito larvacidal activity of Bacillus thuringiensis var. israelensis against uv light has been studied. Results obtained by the live cell counts and the bioassay of residual mosquitocidal activity of B. thuringiensis var. israelensis after exposure to uv radiation showed that melanin is an excellent photoprotective agent.
已经开发出一种生产、分离和纯化黑色素的方法，该黑色素由携带含有酪氨酸酶基因的重组质粒pIJ702的淡紫链霉菌66发酵产生。研究了黑色素对苏云金芽孢杆菌以色列变种杀蚊幼虫活性的紫外线防护效果。通过活细胞计数以及苏云金芽孢杆菌以色列变种在紫外线照射后的残留杀蚊活性生物测定所获得的结果表明，黑色素是一种出色的光保护剂。
