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锝-99m-二乙三胺五乙酸用于肾小球滤过率的测定。

99Tcm-DTPA for the measurement of glomerular filtration rate.

作者信息

Hilson A J, Mistry R D, Maisey M N

出版信息

Br J Radiol. 1976 Sep;49(585):794-6. doi: 10.1259/0007-1285-49-585-794.

DOI:10.1259/0007-1285-49-585-794
PMID:822911
Abstract

Comparison of the blood clearances of 51Cr-EDTA and 99Tcm-Sn-DTPA, in a series of 45 patients with a wide range of glomerular filtration rates, showed that there was a good correlation between the estimates of G.F.R. obtained using the two chelates simultaneously. The single-injection, single-exponential method of G.F.R. estimation was used, with a correction factor of 0.964 for 99Tcm-DTPA, which gave a relationship of G.F.R.Cr = 2.3+G.F.R.Tcml/min with a correlation coefficient of 0.99. 99Tcm-DTPA is a suitable agent for the estimation of glomerular filtration rate.

摘要

对45例肾小球滤过率范围广泛的患者进行的一项研究,比较了51Cr-EDTA和99Tcm-Sn-DTPA的血液清除率,结果显示,同时使用这两种螯合物获得的肾小球滤过率(G.F.R.)估计值之间具有良好的相关性。采用单次注射、单指数法估计G.F.R.,99Tcm-DTPA的校正因子为0.964,得出G.F.R.Cr = 2.3 + G.F.R.Tcml/min的关系,相关系数为0.99。99Tcm-DTPA是一种适用于估计肾小球滤过率的试剂。

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