Smith H L, Hollins G W, Booth I W
Institute of Child Health, University of Birmingham, England.
J Pediatr Gastroenterol Nutr. 1993 Aug;17(2):201-6. doi: 10.1097/00005176-199308000-00013.
Epigastric impedance recording was used to measure gastric half-emptying time (t1/2) of orange squash in 45 healthy infants and children. The relationship between age, body size, and composition and the impedance increase after gastric filling was investigated, together with the effects on half-emptying time of adding fat, increasing viscosity, and increasing osmolality in the test meal. The mean t1/2 for orange squash was 13.5 min. The increase in impedence per unit volume ingested showed a significant inverse relationship with age (r = -0.62, p < 0.001), and with various anthropometric variables (r ranged from -0.48 to -0.80, p < 0.01). No relationship was observed between t1/2 and age, sex, body size, or composition. Addition of 1.25% triglyceride or a 600-fold increase in viscosity of the test meal were both accompanied by a significant lengthening of t1/2 (p = 0.005 and p < 0.001, respectively), but t1/2 did not alter with a fourfold increase in test meal osmolality. The test was well tolerated by all subjects, but its usefulness is limited by susceptibility to movement artefact, and also the necessity to use simple, liquid test meals.
采用上腹部阻抗记录法测量了45名健康婴幼儿和儿童饮用橙汁汽水后的胃半排空时间（t1/2）。研究了年龄、体型和组成与胃充盈后阻抗增加之间的关系，以及试验餐中添加脂肪、增加粘度和增加渗透压对胃半排空时间的影响。橙汁汽水的平均t1/2为13.5分钟。每摄入单位体积后阻抗的增加与年龄呈显著负相关（r = -0.62，p < 0.001），与各种人体测量学变量也呈负相关（r范围为-0.48至-0.80，p < 0.01）。未观察到t1/2与年龄、性别、体型或组成之间存在相关性。试验餐中添加1.25%的甘油三酯或粘度增加600倍均伴随着t1/2的显著延长（分别为p = 0.005和p < 0.001），但试验餐渗透压增加四倍时t1/2未改变。所有受试者对该测试耐受性良好，但其效用受到运动伪影敏感性以及使用简单液体试验餐必要性的限制。
