Garland F C, Garland C F, Gorham E D, Miller M R, Brodine S K, Fallon A, Balazs L L
Division of Epidemiology, Naval Health Research Center, San Diego, California 92186-5122.
J Acquir Immune Defic Syndr (1988). 1993 Nov;6(11):1267-74.
The Navy population is centered around 19 U.S. home ports and several inland duty stations. This is a study of variation in human immunodeficiency virus (HIV) seroconversions in Navy enlisted men by location in the United States, based on 949,570 enzyme-linked immunosorbent assays and 812 seroconversions during 1987-90. Seroconversion rates were higher in personnel in San Francisco (p = 0.0004), Washington, D.C. (p = 0.001), and Orlando, FL (p = 0.04) than in other areas. They were lower in Charleston, SC, New London, CT, Seattle; and Brunswick, ME (p < 0.05). Black men had triple the seroconversion rate of all other men (p < 0.0001). After adjustment for race, age, marital status, and occupation, risk of seroconversion remained high in San Francisco (p = 0.02) and Orlando (p = 0.03). The risk of seroconversion in San Francisco was twice that of other areas in a cohort that did not change location (p = 0.01). In contrast to declining trends overall in the Navy, rates did not decrease in Washington, D.C., a result consistent with previous calculations indicating a delayed second wave of HIV infection in the region.
海军人员主要集中在美国的19个本土港口和几个内陆驻地。这是一项基于1987 - 1990年期间949,570次酶联免疫吸附测定和812次血清转化情况，对美国海军应征入伍男性中人类免疫缺陷病毒（HIV）血清转化的地域差异进行的研究。旧金山（p = 0.0004）、华盛顿特区（p = 0.001）和佛罗里达州奥兰多市（p = 0.04）的人员血清转化率高于其他地区。南卡罗来纳州查尔斯顿、康涅狄格州新伦敦、西雅图以及缅因州不伦瑞克的血清转化率较低（p < 0.05）。黑人男性的血清转化率是所有其他男性的三倍（p < 0.0001）。在对种族、年龄、婚姻状况和职业进行调整后，旧金山（p = 0.02）和奥兰多（p = 0.03）的血清转化风险仍然很高。在一个未更换驻地的队列中，旧金山的血清转化风险是其他地区的两倍（p = 0.01）。与海军总体呈下降趋势相反，华盛顿特区的比率并未下降，这一结果与之前的计算结果一致，表明该地区HIV感染的第二波高峰有所延迟。
