小鼠乳腺细胞不会杀死Yac-1骨髓瘤细胞。

Mouse metrial gland cells do not kill Yac-1 myeloma cells.

作者信息

Stewart I J, Peel S

机构信息

Faculty of Medicine, University of Southampton, UK.

出版信息

J Reprod Immunol. 1993 Jul;24(2):165-71. doi: 10.1016/0165-0378(93)90018-d.

DOI:10.1016/0165-0378(93)90018-d

PMID:8229994

Abstract

Mouse metrial gland cell suspensions, which included granulated metrial gland cells, were assessed for their ability to lyse NK cell target Yac-1 myeloma cells in a 51chromium release cytotoxicity assay. Metrial gland cells did not kill Yac-1 cells even after in vivo stimulation of NK cytotoxicity activity by polyinosilic-cytidilic acid. The precise relationship of granulated metrial gland cells to the NK cell lineage remains to be clarified.

摘要

对包含颗粒化子宫腺细胞的小鼠子宫腺细胞悬液进行评估，通过51铬释放细胞毒性试验检测其裂解NK细胞靶细胞Yac-1骨髓瘤细胞的能力。即使在通过聚肌苷酸-聚胞苷酸对NK细胞毒性活性进行体内刺激后，子宫腺细胞仍未杀死Yac-1细胞。颗粒化子宫腺细胞与NK细胞谱系的确切关系仍有待阐明。