Stewart I J
Faculty of Medicine, University of Southampton, UK.
J Reprod Immunol. 1994 Jan;26(1):1-15. doi: 10.1016/0165-0378(93)00864-p.
The relationship of rodent granulated metrial gland (GMG) cells to the natural killer (NK) cell lineage is reviewed. The antigenic profile of GMG cells provides insufficient evidence to indicate that these cells form part of the NK cell lineage. No good evidence is found that GMG cells are cytotoxic to the NK cytotoxicity target, Yac-1. In Beige mice, which have a defect in the lytic pathway of NK cells, GMG cells were found to kill labyrinthine cytotrophoblast. It is concluded that GMG cells are not a type of NK cell but a novel member of the leucocyte population.
本文综述了啮齿动物颗粒子宫内膜腺（GMG）细胞与自然杀伤（NK）细胞谱系的关系。GMG细胞的抗原谱提供的证据不足，无法表明这些细胞是NK细胞谱系的一部分。没有充分证据表明GMG细胞对NK细胞毒性靶标Yac-1具有细胞毒性。在NK细胞溶解途径存在缺陷的米色小鼠中，发现GMG细胞可杀死迷路滋养层细胞。得出的结论是，GMG细胞不是NK细胞的一种类型，而是白细胞群体中的一个新成员。
