Inbar O, Winstein Y, Daskalovic Y, Levi R, Nueman I
Department of Exercise Medicine, Links Clinic, Edmonton, Alberta, Canada.
Med Sci Sports Exerc. 1993 Oct;25(10):1098-102.
We studied the effects of prone immersion on pulmonary function in children with asthma. Twelve children with asthma were subjected to prone immersion (WET) and standing upright on land (DRY) under controlled conditions regarding temperature and relative humidity of the inhaled air, minute ventilation, respiratory frequency, tidal volume, and the concentration of carbon dioxide in the exhaled air. Eight minutes of isocapnic hyperpnea was performed in random order either in the swimming pool (prone) or on land (upright), with the temperature and relative humidity of the inhaled air kept at 20 +/- 2 degrees C and 10 +/- 2%, respectively. The average accumulated ventilation for the 8 min of hyperpnea was 3151 for the WET treatment and 3101 for the DRY (P > 0.1). Average heart rates were 101 +/- 11 and 115 +/- 17 beats.min-1 for the WET and DRY treatments, respectively (P < 0.05). The decrease in FEV1 (delta FEV1) was 26.3 +/- 16.7% after the WET treatment (compared with pretreatment FEV1), and 26.4 +/- 11.3% after the DRY treatment (P > 0.1 between WET and DRY delta FEV1), with similar trend (insignificant differences between treatments), for delta FVC, delta PEF 50%, and delta PEF 25-75%. It is concluded that airway hyperactivity is not alleviated by whole body prone immersion.
我们研究了俯卧式浸浴对哮喘患儿肺功能的影响。12名哮喘患儿在吸入空气的温度、相对湿度、分钟通气量、呼吸频率、潮气量以及呼出气体中二氧化碳浓度等条件得到控制的情况下,分别进行俯卧式浸浴(WET)和站立于陆地上(DRY)的实验。在游泳池(俯卧)或陆地上(直立)以随机顺序进行8分钟的等碳酸通气过度实验,吸入空气的温度和相对湿度分别保持在20±2℃和10±2%。通气过度8分钟的平均累积通气量,WET组为3151,DRY组为3101(P>0.1)。WET组和DRY组的平均心率分别为101±11次/分钟和115±17次/分钟(P<0.05)。WET组实验后FEV1的下降幅度(相对于实验前的FEV1)为26.3±16.7%,DRY组为26.4±11.3%(WET组和DRY组的FEV1下降幅度之间P>0.1),FVC、PEF 50%以及PEF 25 - 75%的下降趋势相似(两组之间差异不显著)。研究得出结论,全身俯卧式浸浴并不能缓解气道高反应性。