湿度会影响运动诱发性支气管收缩（EIB）患者的运动能力。
Humidity influences exercise capacity in subjects with exercise-induced bronchoconstriction (EIB).
作者信息
Stensrud T, Berntsen S, Carlsen K-H
机构信息
Norwegian School of Sport Sciences, NO-0806 Oslo, Norway.
出版信息
Respir Med. 2006 Sep;100(9):1633-41. doi: 10.1016/j.rmed.2005.12.001. Epub 2006 Jan 30.
RATIONALE
Exercise-induced bronchoconstriction (EIB) increases in cold and dry air and decreases in humid air in subjects with asthma. Few reports have reported on the effect of humid environment upon exercise capacity in subjects with EIB.
OBJECTIVE
The primary aim of the present study was to examine the effect of changing the humidity of the environmental air upon exercise capacity measured by peak oxygen uptake (V O2 peak), peak ventilation (V Epeak) and peak running speed (V peak) and secondarily to assess the influence of environmental humidity upon EIB in subjects suffering from EIB.
METHODS
Twenty subjects (10-45 years old, male/female:13/7) with diagnosed EIB performed exercise testing under standardised, regular environmental conditions, 20.2 degrees C (+/- 1.1) and 40% (+/- 3.3) relative humidity [mean (+/- SD)], and under standardised humid environmental conditions; 19.9 degrees C (+/- 1.0) and 95% (+/- 1.7) relative humidity in random order on separate days. Lung function was measured before and 1, 3, 6, 10 and 15 min after exercise. Heart rate (HR), oxygen uptake (V O2), respiratory gas exchange ratio (RER), breathing frequency (BF) and minute ventilation (V E) were measured during exercise.
RESULTS
V O2 peak and V peak increased significantly from 40% to 95% relative humidity of the environmental air, 4.5% and 5.9%, respectively (P = 0.001). HRpeak increased significantly in the humid environment, while BF(peak) decreased significantly. RERpeak and V Epeak did not change significantly. Post-exercise reduction in FEV1 (DeltaFEV1) and FEF50 (forced expiratory flow at 50% of FVC) (DeltaFEF50) significantly decreased after exercise in a humid environment as compared to regular conditions, DeltaFEV1: 12% (7,17) vs. 24% (19,29) [mean (95% confidence intervals)], respectively, DeltaFEF50: 20% (12,29) vs. 38% (30,46), respectively (P < 0.001).
CONCLUSION
Exercise capacity (V O2 peak and V peak) markedly improved during exercise in humid air in subjects with EIB, whereas EIB was reduced to the half.
原理
在哮喘患者中，运动诱发的支气管收缩（EIB）在寒冷干燥的空气中会加重，而在潮湿的空气中会减轻。关于潮湿环境对EIB患者运动能力影响的报道较少。
目的
本研究的主要目的是探讨改变环境空气湿度对通过峰值摄氧量（V O2峰值）、峰值通气量（V E峰值）和峰值跑步速度（V峰值）测量的运动能力的影响，其次是评估环境湿度对EIB患者EIB的影响。
方法
20名被诊断为EIB的受试者（年龄10 - 45岁，男/女：13/7）在标准化的常规环境条件下（20.2摄氏度（±1.1），相对湿度40%（±3.3）[平均值（±标准差）]）和标准化的潮湿环境条件下（19.9摄氏度（±1.0），相对湿度95%（±1.7）），在不同日期随机顺序进行运动测试。在运动前以及运动后1、3、6、10和15分钟测量肺功能。在运动期间测量心率（HR）、摄氧量（V O2）、呼吸气体交换率（RER）、呼吸频率（BF）和分钟通气量（V E）。
结果
环境空气相对湿度从40%增加到95%时，V O2峰值和V峰值分别显著增加4.5%和5.9%（P = 0.001）。在潮湿环境中HR峰值显著增加，而BF（峰值）显著降低。RER峰值和V E峰值没有显著变化。与常规条件相比，在潮湿环境中运动后FEV1（ΔFEV1）和FEF50（用力肺活量50%时的用力呼气流量）（ΔFEF50）的运动后降低显著减少，ΔFEV1分别为12%（7,17）对24%（19,29）[平均值（95%置信区间）]，ΔFEF50分别为20%（12,29）对38%（30,46）（P < 0.001）。
结论
EIB患者在潮湿空气中运动时运动能力（V O2峰值和V峰值）显著提高，而EIB减轻至一半。
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