Keck P E, McElroy S L, Tugrul K C, Bennett J A, Smith J M
Department of Psychiatry, University of Cincinnati College of Medicine, OH 45267-0559.
Neuropsychobiology. 1993;27(3):150-3. doi: 10.1159/000118971.
Evidence from preclinical studies, preliminary clinical reports, pharmacologic challenge studies and a small number of controlled trials suggests that several antiepileptic agents--valproate, carbamazepine, and clonazepam--may have therapeutic effects in the treatment of patients with panic disorder. We review the theoretical basis and available clinical data supporting the use of these agents in panic disorder.