Barnish G, Maude G H, Bockarie M J, Eggelte T A, Greenwood B M
Medical Research Council Laboratory, Bo, Sierra Leone.
Parassitologia. 1993 Jul;35 Suppl:1-4.
The epidemiology of malaria was investigated in a high rainfall, forested area of southern Sierra Leone. The prevalence rates of P. falciparum, P. malariae and P. ovale in 0-7 year old children, during two surveys conducted over a 12-month period, averaged 61%, 12% and 1% respectively. Groups of febrile children had higher prevalence rates than afebrile groups. Overall, gametocyte rates were approximately one fifth of the trophozoite rates. Malaria accounted for 27% of deaths, as did malnutrition, although no malaria associated deaths occurred in 0-12 month olds. Spleen rates were similar to P. falciparum prevalence rates, and the size did not appear to be related to parasite load at the time of the surveys. Packed cell volumes had normal distributions, with a lower mode after the peak prevalence period. Chloroquine usage increased during the post-rains period compared to the pre-rains period.
在塞拉利昂南部降雨量大的森林地区对疟疾流行病学进行了调查。在为期12个月的两次调查中，0至7岁儿童中恶性疟原虫、三日疟原虫和卵形疟原虫的患病率分别平均为61%、12%和1%。发热儿童组的患病率高于无发热组。总体而言，配子体率约为滋养体率的五分之一。疟疾占死亡人数的27%，营养不良也占27%，不过0至12个月大的婴儿未出现与疟疾相关的死亡。脾肿大率与恶性疟原虫患病率相似，在调查时脾脏大小似乎与寄生虫负荷无关。红细胞压积呈正态分布，在患病率高峰期过后出现较低的众数。与雨季前相比，雨季过后氯喹的使用量有所增加。
