Schmidtke K
Institut für Neuropathologie, Universität München, Germany.
Rev Neurol (Paris). 1993;149(3):213-6.
The case of an alcoholic man is reported who survived a suicidal hanging attempt, and subsequently suffered of amnesia, dementia, apathy and behavioural abnormalities. A clinical diagnosis of hypoxic brain damage was made, but upon autopsy six years later, extensive pseudosystematic thalamic degeneration and mammillary body atrophy were found, indicating a status post Wernicke encephalopathy. Precipitation of the disease is attributed to the synergetic effect of cerebral hypoxia/ischemia and thiamine deficiency.
报告了一例酗酒男子的病例,该男子自杀上吊未遂后存活下来,随后出现失忆、痴呆、冷漠和行为异常。临床诊断为缺氧性脑损伤,但在六年后尸检时,发现广泛的假性系统性丘脑变性和乳头体萎缩,提示韦尼克脑病后遗症。该病的发生归因于脑缺氧/缺血和硫胺素缺乏的协同作用。