Raeman C H, Child S Z, Carstensen E L
Department of Electrical Engineering, University of Rochester, NY 14627.
Ultrasound Med Biol. 1993;19(6):507-12. doi: 10.1016/0301-5629(93)90126-9.
Pressure thresholds for lung hemorrhage by exposure to low-temporal-average-intensity, pulsed ultrasound are of the order of 1 MPa. Earlier evidence suggested that ultrasound modifies the tissue over short periods of time in such a way that the nonthermal action of ultrasound is enhanced. Measurements of thresholds (1) for hemorrhage and (2) for penetration of the hemorrhage through the murine lung in which a given "on-time" was presented to the tissue over periods of time up to 3 min support the hypothesis.
暴露于低时间平均强度脉冲超声下导致肺出血的压力阈值约为1兆帕。早期证据表明，超声在短时间内以增强超声非热作用的方式改变组织。对（1）出血阈值和（2）出血穿透小鼠肺部的阈值的测量支持了这一假设，其中在长达3分钟的时间段内向组织施加了给定的“开启时间”。
