一种与癌胚抗原（CEA）发生交叉反应的猴抗原。
A monkey antigen crossreacting with carcinoembryonic antigen, CEA.
作者信息
Engvall E, Vuento M, Ruoslahti E
出版信息
Br J Cancer. 1976 Oct;34(4):341-5. doi: 10.1038/bjc.1976.176.
Abstract
Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusion against anti-CEA or anti-NCA. Extracts of monkey tissues inhibited in radioimmunoassays measuring human NCA. It is possible that monkey foetuses and colonic tumours contain CEA.
摘要
正常猴组织中发现含有一种抗原，该抗原与人类消化道癌胚抗原（CEA）发生免疫交叉反应。当用抗CEA或抗NCA进行免疫扩散试验时，猴抗原与人类正常交叉反应抗原（NCA）完全或部分相同。猴组织提取物在放射免疫测定中可抑制人NCA。猴胎儿和结肠肿瘤可能含有CEA。
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