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伴随大鼠辐射诱导小肠腺癌的癌胚蛋白

Oncofetal protein accompanying irradiation-induced small-bowel adenocarcinoma in the rat.

作者信息

Stevens R H, England C W, Osborne J W, Cheng H F, Richerson H B

出版信息

J Natl Cancer Inst. 1975 Oct;55(4):1011-3. doi: 10.1093/jnci/55.4.1011.

DOI:10.1093/jnci/55.4.1011
PMID:52717
Abstract

A tumor-associated protein was found in tissue derived from an X-irradiation-induced adenocarcinoma in the small bowel of the rat. The protein was associated with the cell membranes of the tumor tissue. It shared common antigenic determinants both with a rat fetal protein and a perchloric acid-soluble protein isolated from the serum of the tumor-bearing rat.

摘要

在源自大鼠小肠X线照射诱导的腺癌组织中发现了一种肿瘤相关蛋白。该蛋白与肿瘤组织的细胞膜相关。它与大鼠胎儿蛋白以及从荷瘤大鼠血清中分离出的一种高氯酸可溶性蛋白具有共同的抗原决定簇。

相似文献

1
Oncofetal protein accompanying irradiation-induced small-bowel adenocarcinoma in the rat.伴随大鼠辐射诱导小肠腺癌的癌胚蛋白
J Natl Cancer Inst. 1975 Oct;55(4):1011-3. doi: 10.1093/jnci/55.4.1011.
2
Identification and characterization of a circulating tumor-associated oncofetal protein from a radiation-induced adenocarcinoma of the rat small bowel.
Cancer Res. 1976 Sep;36(9 pt.1):3260-4.
3
Lymphocyte cytotoxicity in x-irradiation-induced rat small bowel adenocarcinoma. III. Blocking by 3 M KCL extract.
J Immunol. 1978 Jan;120(1):335-9.
4
Lymphocyte cytotoxicity in X-irradiation-induced adenocarcinoma of the rat small bowel. I. Measurement of target cell destruction by release of radioiodinated membrane proteins: brief communication.
J Natl Cancer Inst. 1977 Oct;59(4):1315-9. doi: 10.1093/jnci/59.4.1315.
5
Lymphocyte cytotoxicity in the X-irradiation induced rat small bowel adenocarcinoma. II. Presence of cytotoxic lymphocytes in irradiated animals.X射线诱导的大鼠小肠腺癌中的淋巴细胞细胞毒性。II. 受辐照动物中细胞毒性淋巴细胞的存在
Immunol Commun. 1978;7(3):281-93. doi: 10.3109/08820137809025473.
6
Vitamin A contents of rat intestinal epithelium and jejunal mucinous adenocarcinoma.大鼠肠上皮和空肠黏液腺癌中的维生素A含量
J Natl Cancer Inst. 1977 Jun;58(6):1643-5. doi: 10.1093/jnci/58.6.1643.
7
Lymphocyte cytotoxicity in X-irradiation induced rat small bowel adenocarcinoma. IV. Activation of cellular immunity by X irradiation.X射线诱导大鼠小肠腺癌中的淋巴细胞细胞毒性。IV. X射线对细胞免疫的激活作用。
Radiology. 1979 Jan;130(1):237-40. doi: 10.1148/130.1.237.
8
Proceedings: Biochemical identification of a protein associated with rat tumour and embryo cell membranes.论文集:与大鼠肿瘤和胚胎细胞膜相关的一种蛋白质的生化鉴定
Br J Cancer. 1975 Aug;32(2):240-1. doi: 10.1038/bjc.1975.156.
9
Antibody-dependent cell-mediated cytotoxicity in X-irradiation-induced adenocarcinoma of the rat small bowel.X射线诱导的大鼠小肠腺癌中的抗体依赖性细胞介导的细胞毒性
Radiat Res. 1981 Sep;87(3):635-45.
10
Adenosine 3',5'-cyclic monophosphate levels in x-ray-induced small-bowel adenocarcinoma in the rat.大鼠X射线诱导的小肠腺癌中3',5'-环磷酸腺苷水平
J Natl Cancer Inst. 1976 Jul;57(1):43-5. doi: 10.1093/jnci/57.1.43.

引用本文的文献

1
Identification of a common oncofoetal protein in x-ray and chemically induced rat gastrointestinal tumours.在X射线和化学诱导的大鼠胃肠道肿瘤中鉴定一种常见的癌胚蛋白。
Br J Cancer. 1981 Jun;43(6):817-25. doi: 10.1038/bjc.1981.120.
2
Cell-mediated cytotoxicity expressed by lymphoid cells from rats with asbestos-induced peritoneal mesothelioma towards rat fetal cell.石棉诱导的大鼠腹膜间皮瘤来源的淋巴细胞对大鼠胎儿细胞的细胞介导细胞毒性。
Environ Health Perspect. 1983 Sep;51:91-6. doi: 10.1289/ehp.835191.
3
Scintigraphy and distribution of labeled antibodies in rats with tumors.
肿瘤大鼠的闪烁扫描及标记抗体的分布
Eur J Nucl Med. 1982;7(1):28-34. doi: 10.1007/BF00275241.
4
A monkey antigen crossreacting with carcinoembryonic antigen, CEA.一种与癌胚抗原(CEA)发生交叉反应的猴抗原。
Br J Cancer. 1976 Oct;34(4):341-5. doi: 10.1038/bjc.1976.176.