• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

恒河猴(猕猴)输卵管中的氧张力。

Oxygen tension in the oviduct of the rhesus monkey (Macaca mulatta).

作者信息

Maas D H, Storey B T, Mastroianni L

出版信息

Fertil Steril. 1976 Nov;27(11):1312-7. doi: 10.1016/s0015-0282(16)42201-6.

DOI:10.1016/s0015-0282(16)42201-6
PMID:824161
Abstract

The oxygen tension in the oviductal fluid of adult female rhesus monkeys was measured by means of miniaturized, flexible, oxygen probes between days 5 and 22 of the menstrual cycle. In the follicular phase, the value was very low, less than 10 Torr. At the time of ovulation to about 5 to 7 days thereafter, the oxygen tension in the tube on the side of ovulation increased within approximately 2 minutes after insertion of the oxygen probe from the low level to the same value as in the blood. In the contralateral oviduct, the oxygen tension remained at less than 10 Torr. These findings suggest that, in the absence of ovulation, the blood-oxygen supply of the oviduct provides the exact oxygen requirement of oviductal tissue, with no excess oxygen available for the tubal fluid. At and shortly after ovulation, the presence of a probe stimulates, by an unknown mechanism, an increase in the oxygen tension in the oviductal fluid which provides an environment sufficiently well-oxygenated for gamete survival, fertilization, and subsequent further development of the embryo. We suggest that the ovum entering the oviduct provides a similar stimulus with a similar result by the same unknown mechanism.

摘要

在成年雌性恒河猴月经周期的第5至22天,使用小型化、柔性氧探头测量输卵管液中的氧张力。在卵泡期,该值非常低,低于10托。在排卵时及之后约5至7天,排卵侧输卵管内的氧张力在插入氧探头后约2分钟内从低水平升至与血液中相同的值。在对侧输卵管中,氧张力保持低于10托。这些发现表明,在不排卵的情况下,输卵管的血液供氧提供了输卵管组织确切的氧需求,没有多余的氧供输卵管液使用。在排卵时及排卵后不久,探头的存在通过未知机制刺激输卵管液中氧张力增加,从而为配子存活、受精及随后胚胎的进一步发育提供了充分氧合的环境。我们认为,进入输卵管的卵子通过相同的未知机制提供了类似的刺激并产生类似的结果。

相似文献

1
Oxygen tension in the oviduct of the rhesus monkey (Macaca mulatta).恒河猴(猕猴)输卵管中的氧张力。
Fertil Steril. 1976 Nov;27(11):1312-7. doi: 10.1016/s0015-0282(16)42201-6.
2
Hydrogen ion and carbon dioxide content of the oviductal fluid of the rhesus monkey (Macaca mulatta).恒河猴(猕猴)输卵管液中的氢离子和二氧化碳含量。
Fertil Steril. 1977 Sep;28(9):981-5.
3
Effects of prostaglandins on oviductal motility and egg transport.前列腺素对输卵管运动和卵子运输的影响。
Gynecol Invest. 1975;6(3-4):186-205. doi: 10.1159/000301516.
4
Oviductal fluid protein patterns in the rhesus monkey (Macaca mulatta) during the menstrual cycle.恒河猴(猕猴)月经周期中的输卵管液蛋白质模式。
Reprod Fertil Dev. 1992;4(2):249-57. doi: 10.1071/rd9920249.
5
Cyclic fluctuation in noradrenaline transmitter of the monkey oviduct.猕猴输卵管去甲肾上腺素递质的周期性波动。
Acta Obstet Gynecol Scand. 1977;56(2):139-53. doi: 10.3109/00016347709158356.
6
[Immunology of the pre-implantation phase in pregnancy. Protein content and antigenic properties of the oviduct-secretion in mammals].[妊娠植入前期的免疫学。哺乳动物输卵管分泌物的蛋白质含量及抗原特性]
Fortschr Med. 1976 Nov 4;94(31):1765-70.
7
Cyclic changes in the human fallopian tube isthmus and their functional importance.人类输卵管峡部的周期性变化及其功能重要性。
Am J Obstet Gynecol. 1980 Feb 1;136(3):292-308. doi: 10.1016/0002-9378(80)90853-4.
8
Prostaglandins in the human fallopian tube.人输卵管中的前列腺素。
Fertil Steril. 1974 Mar;25(3):250-5.
9
Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits.恒河猴、仓鼠和兔子输卵管及子宫中的氧张力。
J Reprod Fertil. 1993 Nov;99(2):673-9. doi: 10.1530/jrf.0.0990673.
10
Stimulation of rhesus monkey (Macaca mulatta) proacrosin activation by oviduct fluid.输卵管液对恒河猴(猕猴)前顶体蛋白酶激活的刺激作用。
J Reprod Fertil. 1980 Jul;59(2):479-84. doi: 10.1530/jrf.0.0590479.

引用本文的文献

1
Oxidative Stress and Assisted Reproduction: A Comprehensive Review of Its Pathophysiological Role and Strategies for Optimizing Embryo Culture Environment.氧化应激与辅助生殖:对其病理生理作用及优化胚胎培养环境策略的全面综述
Antioxidants (Basel). 2022 Feb 28;11(3):477. doi: 10.3390/antiox11030477.
2
Proteomics Analysis Reveals that Warburg Effect along with Modification in Lipid Metabolism Improves In Vitro Embryo Development under Low Oxygen.蛋白质组学分析表明,低氧条件下,糖酵解增强以及脂代谢修饰可提高体外胚胎发育能力。
Int J Mol Sci. 2020 Mar 14;21(6):1996. doi: 10.3390/ijms21061996.
3
Effects of dynamic oxygen concentrations on the development of mouse pre- and peri-implantation embryos using a double-channel gas supply incubator system.
使用双通道气体供应培养箱系统研究动态氧浓度对小鼠植入前和植入周围胚胎发育的影响。
Clin Exp Reprod Med. 2019 Dec;46(4):189-196. doi: 10.5653/cerm.2019.00514. Epub 2019 Dec 1.
4
Pluripotent Stem Cell Metabolism and Mitochondria: Beyond ATP.多能干细胞代谢与线粒体:超越三磷酸腺苷
Stem Cells Int. 2017;2017:2874283. doi: 10.1155/2017/2874283. Epub 2017 Jul 19.
5
Oxygen tension in embryo culture: does a shift to 2% O in extended culture represent the most physiologic system?胚胎培养中的氧张力:在延长培养中转换至2%的氧气浓度是否代表最生理的系统?
J Assist Reprod Genet. 2017 Mar;34(3):309-314. doi: 10.1007/s10815-017-0880-z. Epub 2017 Feb 8.
6
Preimplantation stress and development.植入前应激与发育。
Birth Defects Res C Embryo Today. 2012 Dec;96(4):299-314. doi: 10.1002/bdrc.21022.
7
IVF/ICSI outcomes after culture of human embryos at low oxygen tension: a meta-analysis.低氧张力培养人类胚胎对体外受精/卵胞浆内单精子注射结局的影响:荟萃分析。
Reprod Biol Endocrinol. 2011 Nov 1;9:143. doi: 10.1186/1477-7827-9-143.
8
Immunohistochemical assessment of intrinsic and extrinsic markers of hypoxia in reproductive tissue: differential expression of HIF1α and HIF2α in rat oviduct and endometrium.生殖组织中缺氧内在和外在标志物的免疫组织化学评估:HIF1α 和 HIF2α 在大鼠输卵管和子宫内膜中的差异表达。
J Mol Histol. 2011 Aug;42(4):341-54. doi: 10.1007/s10735-011-9338-2. Epub 2011 Jul 6.
9
Oxygen, a Key Factor Regulating Cell Behavior during Neurogenesis and Cerebral Diseases.氧气,调节神经发生和脑部疾病期间细胞行为的关键因素。
Front Mol Neurosci. 2011 Apr 4;4:5. doi: 10.3389/fnmol.2011.00005. eCollection 2011.
10
Antioxidants, Oxyrase, and mitochondrial uncoupler 2,4-dinitrophenol improved postthaw survival of rhesus monkey sperm from ejaculates with low cryosurvival.抗氧化剂、Oxyrase 和线粒体解偶联剂 2,4-二硝基苯酚提高了冷冻保存后低冷冻存活率的恒河猴精子的复苏后存活率。
Fertil Steril. 2010 Nov;94(6):2359-61. doi: 10.1016/j.fertnstert.2010.04.017.