Colangelo P, Piattelli A, Barrucci S, Trisi P, Formisano G, Caiazza S
Dental School, University G. D'Annunzio, Chieti, Italy.
Implant Dent. 1993;2(2):101-5. doi: 10.1097/00008505-199305000-00007.
Artificial cross-shaped intrabony defects were created in the mandibles of 12 rabbits and the cavities covered with Type I highly cross-linked resorbable collagen membranes for 30 days. Similar cavities were prepared in three control animals and left uncovered for the same time period. Morphological and analytical data were obtained by means of light microscopy, scanning electron microscopy, and x-ray energy-dispersive spectrometry. After the experimental period, the membrane covered cavities were completely filled with regenerated bone. In the control specimens, the artificial cavities were occupied by fibrous connective tissue.
在12只兔子的下颌骨中制造人工十字形骨内缺损，并用I型高度交联可吸收胶原膜覆盖缺损腔30天。在3只对照动物中制备类似的缺损腔，在相同时间段内不覆盖任何材料。通过光学显微镜、扫描电子显微镜和X射线能量色散光谱法获得形态学和分析数据。实验期结束后，膜覆盖的缺损腔完全被再生骨填充。在对照标本中，人工缺损腔被纤维结缔组织占据。
