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[利用光学显微镜和电子显微镜对皮肤苔藓样淀粉样变进行组织化学研究]

[Histochemical studies of cutaneous lichen amyloidosis using light and electron microscopy].

作者信息

He Z

机构信息

PUMC Hospital.

出版信息

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1993 Apr;15(2):115-8.

PMID:8242818
Abstract

Ten cases of cutaneous lichen amyloidosis are reported. Amyloid deposits were found to be limited to the papillary dermis. The amyloid masses were often fissured and had an amorphous eosinophilic globular appearance. The protein was confirmed by histochemistry as amyloid-associated protein. The epidermal origin of the amyloid deposit has been confirmed by electron microscopy. The amyloid deposit was of variable island structure, accompanied by filaments.

摘要

报告了10例皮肤苔藓样淀粉样变。发现淀粉样沉积物局限于乳头真皮层。淀粉样物质团块常出现裂隙，呈无定形嗜酸性球状外观。经组织化学证实该蛋白为淀粉样相关蛋白。淀粉样沉积物的表皮起源已通过电子显微镜得到证实。淀粉样沉积物呈可变的岛状结构，并伴有细丝。

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