Sinicco A, Gagliano P, Caramello P, Fora R, Sciandra M, Novero D
Institute of Infectious Disease, University of Turin, Italy.
Cutis. 1993 Sep;52(3):173-6.
We report a case of eruptive metastases to the skin of the face and neck from a hitherto unknown gastric carcinoma, occurring in a fifty-two-year-old man (a regular blood donor), about six months after he contracted human immunodeficiency virus-1 infection. The eruption, consisting of more than thirty pea-sized cutaneous nodules appeared within about twenty days. The patient complained of epigastric pain and weight loss. Histologic examination showed signet-ring cells of gastric carcinoma metastases. Gastroscopic examination showed a widely infiltrating tumor. No metastases were found elsewhere after a careful screening. Immunologic variables were only slightly altered. This case and a brief review suggest that gastric carcinomas, possibly as well as other coincidental tumors, may present atypically during human immunodeficiency virus-1 infection.
我们报告了一例发生在一名52岁男性（一名定期献血者）面部和颈部皮肤的爆发性转移瘤病例，该转移瘤来自此前未知的胃癌，发生在他感染人类免疫缺陷病毒1型约6个月后。皮疹由30多个豌豆大小的皮肤结节组成，在约20天内出现。患者主诉上腹部疼痛和体重减轻。组织学检查显示为胃癌转移的印戒细胞。胃镜检查显示为广泛浸润性肿瘤。经过仔细筛查，未在其他部位发现转移。免疫变量仅略有改变。该病例及简要综述表明，胃癌以及可能的其他并发肿瘤在人类免疫缺陷病毒1型感染期间可能会出现非典型表现。
