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[急性氟中毒及高压氧治疗时肝脏能量代谢参数的变化]

[Changes in energy metabolism parameters of the liver in acute fluoride intoxication and hyperbaric oxygenation].

作者信息

Tyrtyshnikov I M, Gorishna O V

出版信息

Fiziol Zh (1978). 1993 Jul-Aug;39(4):91-4.

PMID:8243724
Abstract

Examinations of energetic metabolism in liver of white rats with acute fluoride intoxication were carried out in acute and recovering periods. The influence of hyperbaric oxygenation on the change of energetic metabolism indices and on survival rates of animals has been studied. Hyperbaric oxygenation greatly prevented profound metabolic disturbances, in particular, ATP, increased detoxic in liver intensifying energetic forming processes. The survival rate of animals under the influence of course of HBO increased by 27% during first 72 hours. It was determined that HBO has an effective influence on the course of recovering period during fluoride intoxication.

摘要

在急性氟中毒的急性期和恢复期对白鼠肝脏的能量代谢进行了检测。研究了高压氧疗对能量代谢指标变化及动物存活率的影响。高压氧疗极大地预防了严重的代谢紊乱,尤其是三磷酸腺苷(ATP),增强了肝脏的解毒作用并强化了能量生成过程。在高压氧疗疗程影响下,动物在前72小时内的存活率提高了27%。已确定高压氧疗对氟中毒恢复期的病程有有效影响。

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