Kilinç Y
Department of Pediatrics, Cukurova University Faculty of Medicine, Adana, Turkey.
Turk J Pediatr. 1993 Apr-Jun;35(2):105-9.
Plasma, erythrocyte and urinary selenium levels were determined in 21 sickle cell homozygote patients, 20 siblings with sickle cell traits, 29 parents and in 21 healthy controls with an HbAA pattern. The mean levels of plasma and erythrocyte selenium and the daily urinary selenium depletion were found to be lower in the HbSS patients than in the controls (p < 0.02; p < 0.001; p < 0.001, respectively). Urinary selenium depletion was found to be lower in the sickle cell trait siblings than in the controls (p < 0.001), but the plasma and erythrocyte selenium levels were close to normal values (p > 0.05). The mean erythrocyte selenium levels were found to be decreased in the parents as compared with the controls (p < 0.05), which indicates that urinary selenium losses may be replenished primarily by sources in the plasma and in the erythrocytes before stores in the other parts of the body are used.
测定了21例镰状细胞纯合子患者、20例具有镰状细胞性状的同胞、29例父母以及21例具有HbAA模式的健康对照者的血浆、红细胞和尿硒水平。发现HbSS患者的血浆和红细胞硒平均水平以及每日尿硒消耗量低于对照组（分别为p < 0.02；p < 0.001；p < 0.001）。发现具有镰状细胞性状的同胞的尿硒消耗量低于对照组（p < 0.001），但其血浆和红细胞硒水平接近正常范围（p > 0.05）。与对照组相比，发现父母的红细胞硒平均水平降低（p < 0.05），这表明在身体其他部位的储存被利用之前，尿硒损失可能主要由血浆和红细胞中的来源补充。
