Bermúdez de la Vega J A, Gómez Calzado A, Sobrino Toro M, Alejo Garcia-Mauricio A, Romero Cachaza J, González Hachero J
Cátedra de Pediatría y Puericultura de la Facultad de Medicina, Hospital Universitario Virgen Macarena, Sevilla.
An Esp Pediatr. 1993 Sep;39(3):214-8.
We have studied 50 children affected with acute meningococcal disease (AMD). The ages of the children varied between 4 months and 12.58 years, with a mean age of 4.58 years. By using the shock state and DIC syndrome, both of which are indications of the severity of the illness, an evaluation of the discriminatory capacity was done with regard to significantly associate variables and 3 scores, Bjorvatn, Leclerc and PRISM, throughout 8 intervals within the first 48 hours of hospital treatment. We observed a very high survival rate (98%) associated with the early treatment for shock. Leukopenia and disseminated purpura were the best variables in order to discriminate shock and DIC, respectively. The greatest capacity for the diagnosis of the shock state and DIC syndrome were registered during the 0-6 hour period and the 0-12 hour period, respectively. The prognosis improved if the child remained alive 12 hours after the treatment had begun.
我们研究了50名患有急性脑膜炎球菌病（AMD）的儿童。这些儿童的年龄在4个月至12.58岁之间，平均年龄为4.58岁。通过使用休克状态和弥散性血管内凝血（DIC）综合征这两种疾病严重程度的指标，在住院治疗的前48小时内，针对显著相关变量和3种评分（比约瓦特恩评分、勒克莱尔评分和小儿死亡风险评分（PRISM））进行了鉴别能力评估。我们观察到与休克的早期治疗相关的存活率非常高（98%）。白细胞减少和弥漫性紫癜分别是鉴别休克和DIC的最佳变量。休克状态和DIC综合征的最大诊断能力分别在0 - 6小时和0 - 12小时期间记录到。如果儿童在治疗开始后12小时仍存活，预后会有所改善。
