Kee F, Gaffney B, Currie S, O'Reilly D
Department of Epidemiology and Public Health, Queen's University, Belfast.
BMJ. 1993 Nov 20;307(6915):1305-7. doi: 10.1136/bmj.307.6915.1305.
To determine the effects of patient's sex and area's material deprivation on utilisation rates of coronary catheterisation and angiography in the investigation of ischaemic heart disease.
Retrospective analysis of routinely collected hospital statistics.
Acute hospitals throughout Northern Ireland.
24,179 episodes of patients discharged from hospital with a primary diagnosis of ischaemic heart disease and 1270 episodes relating to patients with an underlying diagnosis of ischaemic heart disease who had either coronary catheterisation or angiography.
Age standardised admission rates for heart disease and age standardised utilisation rates for catheterisation or angiography, or both, for 566 electoral wards ranked by Townsend "deprivation" scores.
Catheterisation-angiography rates in men were over fivefold those of women, ranging from 85.5/100,000 v 16/100,000 in patients from "well off" areas to 123/100,000 v 22/100,000 for patients from deprived areas. After admission rates for heart disease were controlled for, the overall rate ratio for women was 0.48 (95% confidence interval 0.38 to 0.60). After differential admission rates for heart disease and other potential clinical confounders were controlled for, the investigation rates of patients from the least and most "deprived" areas were not significantly different (rate ratio 1.04 (0.87 to 1.25)).
Although investigation rates were significantly lower in women than in men, further clinical data would be required before labelling this underutilisation as evidence of bias. There was no significant difference in invasive investigation rates for heart disease in areas of varying deprivation or affluence.
确定患者性别和地区物质匮乏程度对缺血性心脏病调查中冠状动脉导管插入术和血管造影术使用率的影响。
对常规收集的医院统计数据进行回顾性分析。
北爱尔兰各地的急症医院。
24179例以缺血性心脏病为主要诊断出院的患者,以及1270例以缺血性心脏病为潜在诊断且接受了冠状动脉导管插入术或血管造影术的患者。
按汤森“匮乏”评分排序的566个选区病房的年龄标准化心脏病入院率以及导管插入术或血管造影术(或两者)的年龄标准化使用率。
男性的导管插入术-血管造影术使用率是女性的五倍多,从“富裕”地区患者的85.5/10万对16/10万到贫困地区患者的123/10万对22/10万不等。在控制心脏病入院率后,女性的总体率比为0.48(95%置信区间0.38至0.60)。在控制心脏病和其他潜在临床混杂因素的差异入院率后,最贫困和最不贫困地区患者的检查率无显著差异(率比1.04(0.87至1.25))。
尽管女性的检查率显著低于男性,但在将这种利用不足标记为偏倚证据之前,还需要进一步的临床数据。不同贫困或富裕地区心脏病的侵入性检查率没有显著差异。