Freiss G, Prébois C, Vignon F
INSERM Unit 148 on Hormones and Cancer, Montpellier, France.
Breast Cancer Res Treat. 1993;27(1-2):57-68. doi: 10.1007/BF00683193.
Over the past two decades, the simple model for control of breast cancer growth involving one or two factors acting directly or indirectly via endocrine pathways has turned into a complex model implicating numerous interacting factors and the diverse cell populations constituting breast tumors. Current approaches to breast cancer therapy now require integration of these multiple parameters and enhanced understanding of the different levels of their intricate interactions.
在过去二十年里，乳腺癌生长控制的简单模型，即涉及一两个通过内分泌途径直接或间接起作用的因素，已转变为一个复杂模型，其中包含众多相互作用的因素以及构成乳腺肿瘤的不同细胞群体。目前的乳腺癌治疗方法现在需要整合这些多个参数，并加深对它们复杂相互作用不同层面的理解。
