Bangs M J, Annis B A, Bahang Z H, Hamzah N, Arbani P R
US Naval Medical Research Unit No. 2, Jakarta, Indonesia.
Southeast Asian J Trop Med Public Health. 1993 Jun;24(2):357-62.
Anopheles koliensis, an important malaria vector in the interior region of Irian Jaya, Indonesia, was evaluated for susceptibility to three different insecticide compounds using the standard World Health Organization diagnostic test kit and pretreated impregnated papers. A series of tests were conducted in Arso PIR I, a transmigrant settlement 60 km south of Jayapura, from January 1988 to May 1989. All compounds were tested at the recommended diagnostic dosage and exposure time. An. koliensis were susceptible to 1.0% fenitrothion at two hour exposure (N = 358) and 5.0% malathion at one hour exposure (N = 371) after the 24-hour holding period. Significant resistance to DDT was observed in both the An. koliensis and Culex quinquefasciatus populations. Approximately 30% of the An. koliensis population (N = 468) was resistant to 4% DDT at both one and two hour exposures. These findings indicate that routine use of DDT in Arso PIR I for indoor residual house spraying may be of limited effectiveness, in part, because of physiological resistance. However, use of an alternative insecticide will be more expensive and might prove equally ineffective because of the exophilic behavior of the species. This is the first confirmed report from repeated observations of DDT resistance in An. koliensis from Indonesia.
科利按蚊是印度尼西亚伊里安查亚内陆地区一种重要的疟疾传播媒介，使用世界卫生组织标准诊断试剂盒和预处理过的浸渍纸对其进行了三种不同杀虫剂化合物的敏感性评估。1988年1月至1989年5月，在贾亚普拉以南60公里处的一个移民定居点阿尔索PIR I进行了一系列测试。所有化合物均在推荐的诊断剂量和暴露时间下进行测试。在24小时的饲养期后，科利按蚊在两小时暴露于1.0%杀螟硫磷（N = 358）和一小时暴露于5.0%马拉硫磷（N = 371）时表现出易感性。在科利按蚊和致倦库蚊种群中均观察到对滴滴涕的显著抗性。约30%的科利按蚊种群（N = 468）在一小时和两小时暴露于4%滴滴涕时均具有抗性。这些结果表明，在阿尔索PIR I常规使用滴滴涕进行室内滞留喷洒可能效果有限，部分原因是生理抗性。然而，使用替代杀虫剂成本会更高，而且由于该物种的嗜外行为，可能同样无效。这是来自印度尼西亚对科利按蚊中滴滴涕抗性重复观察的第一份确认报告。
