Synnott M, Morse D L, Maguire H, Majid F, Plummer M, Leicester M, Threlfall E J, Cowden J
PHLS Communicable Disease Surveillance Centre, London.
Epidemiol Infect. 1993 Dec;111(3):473-81. doi: 10.1017/s0950268800057204.
During October 1992 an increase in the number of isolates of Salmonella mikawasima, a rare serotype, was noted including a cluster of nine cases in the South West Thames region. A case control study was conducted and univariate analysis showed a statistical association between illness and eating at take-away A for cases compared with household controls (P = 0.003) and with neighbourhood controls (P = 0.0245). Cases were also more likely to have eaten kebabs than were controls or average take-away A customers, implicating doner kebabs as the most likely vehicle of infection. Plasmid profile analysis of the nine cases' isolates showed them to be indistinguishable and to be characterized by a single plasmid of approximately 60 MDa. The original source of the Salmonella mikawasima contamination was not determined, but food preparation practices for kebabs at take-away A were insufficient to protect against illness if contaminated. This outbreak was only recognized because of the unusual serotype, but could be an indication of a more widespread problem with doner kebabs.
1992年10月期间,发现一种罕见血清型的三波川沙门氏菌分离株数量有所增加,其中包括泰晤士河西南部地区的9例聚集性病例。开展了一项病例对照研究,单因素分析显示,与家庭对照相比,病例发病与在A外卖店就餐之间存在统计学关联(P = 0.003),与邻里对照相比也存在统计学关联(P = 0.0245)。与对照或A外卖店的普通顾客相比,病例食用烤肉串的可能性也更大,这表明旋转烤肉串最有可能是感染源。对9例病例的分离株进行质粒图谱分析,结果显示它们无法区分,且其特征是含有一个约60 MDa的单一质粒。三波川沙门氏菌污染的最初来源尚未确定,但如果受到污染,A外卖店烤肉串的食品制备做法不足以预防疾病。此次疫情仅因血清型罕见才被发现,但这可能表明旋转烤肉串存在更广泛的问题。